Shining Light on Madness
So far, researchers have identified hundreds of genetic variants associated with increased risk for schizophrenia. Some of the mutations appear to be common, while some rare variants seem to cause the same symptoms as those experienced by individuals with a completely different set of rare mutations. “Whether you think the extreme genetic complexity of brain disorders portends well for drug discovery depends on whether you’re a pessimist or an optimist,” said Pamela Sklar, MD, Professor of Psychiatry, Genetics and Genomic Sciences, and Neuroscience at the Icahn School of Medicine at Mount Sinai.
-Dr. Pamela Sklar, Professor, Psychiatry, Genetics and Genomic Sciences, Neuroscience, Icahn School of Medicine at Mount Sinai