Bio IT World - Gene Deletions May Be Implicated in Autism - Aaron Krol

 – October 3, 2013  –– 

About one in 100 children have autism spectrum disorder. It is known to run in families, but scientists have not been able to identify an exact cause. Joseph Buxbaum, MD, from the Icahn School of Medicine at Mount Sinai School, compared the genetic profiles of 431 people with autism and 329 without and found that people who lacked certain genes could have "mis-wiring" between nerve cells in the brain. "This is the first finding that small deletions impacting one or two genes appear to be common in autism, and that these deletions contribute to risk of development of this disorder," says Dr. Buxbaum. The study was published in American Journal of Human Genetics.
-Dr. Joseph Buxbaum, Professor, Psychiatry, Genetic and Genomic Sciences, Neuroscience, Icahn School of Medicine at Mount Sinai
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