Low Testosterone and Muscle Mass

 – April 8, 2014  –– 

Testosterone helps build muscle, and low testosterone can cause loss of muscle mass. “Loss of muscle is called muscle wasting, and it’s a late sign of low testosterone. But even before you notice muscle wasting, you may feel weaker and less energetic,” said Ronald Tamler, MD, Associate Professor of Medicine, Endocrinology, Diabetes and Bone Disease, and Clinical Director of the Mount Sinai Diabetes Center at the Mount Sinai Health System. “Muscle cells have receptors for testosterone called androgen receptors. When testosterone binds to the receptors, muscle fibers are maintained. Without testosterone, maintenance stops and muscle is degraded.”

-Dr. Fred Lublin, Professor, Neurology, Icahn School of Medicine at Mount Sinai, Director, Corinne Goldsmith Dickinson Center for Multiple Sclerosis, the Mount Sinai Health System

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