- Mount Sinai Researchers Develop A Multi-Target Approach To Treating Tumors

 – June 10, 2012  –– 

Researchers from Mount Sinai School of Medicine developed a cancer model built in the fruit fly Drosophila, then used it to create a whole new approach to the discovery of cancer treatments. The result is an investigational compound AD80 that precisely targets multiple cancer genes. Tested in mouse models, the drug proved far more effective and less toxic than standard cancer drugs, which generally focus on a single target. "We've come up with one drug that hits multiple targets through 'rational polypharmacology,' and our approach represents a new concept we believe will have great success in suppressing tumors," said Ross L. Cagan, Ph.D., Professor and Associate Dean at Mount Sinai School of Medicine.
- Dr. Ross L. Cagan, Associate Dean Of The Graduate School Of Biological Sciences, Professor Developmental and Regenerative Biology, Oncological Sciences, and Ophthalmology, Mount Sinai School of Medicine
Learn more: