Age-Linked Memory Loss May Be Worse for Men, Study Finds

 – March 16, 2015  –– 

A new study finds that nearly everyone will suffer more memory lapses as they age, with men being more vulnerable to failing memory than women. The study also reported that people's memory skills and brain volume typically decline with age -- and, surprisingly, it seems to have little to do with the buildup of brain "plaques" that mark Alzheimer's disease, the study suggests. Mary Sano, PhD, an Alzheimer's researcher at The Mount Sinai Hospital, in New York City, said the findings are "exciting." A lot of research aimed at preventing Alzheimer's has focused on amyloid buildup, Sano noted. But this study, she said, suggests other avenues -- including "interventions that focus on brain volume" -- should be explored, too. And how do you change brain volume? Exercise is one possibility. "Research has shown that physical activity may slow the brain volume loss that comes with aging," Sano said.

-Mary Sano, PhD, Professor, Psychiatry, Associate Dean for Clinical Research, Director of Alzheimer’s Disease Research, Icahn School of Medicine at Mount Sinai

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