An Evolutionary Approach Reveals New Clues toward Understanding the Roots of Schizophrenia


 – February 24, 2015  –– 

Is mental illness simply the evolutionary toll humans have to pay in return for our unique and superior cognitive abilities when compared to all other species? But if so, why have often debilitating illnesses like schizophrenia persisted throughout human evolutionary history when the affects can be quite negative on an individual's chances of survival or reproductive success? In a new study appearing in Molecular Biology and Evolution, The Mount Sinai Hospital researcher Joel Dudley has led a new study that suggests that the very changes specific to human evolution may have come at a cost, contributing to the genetic architecture underlying schizophrenia traits in modern humans.

- Dr. Joel Dudley, Assistant Professor, Genetics and Genomic Sciences, Population Health Science Policy, Icahn School of Medicine at Mount Sinai

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