Protein Found that Keeps Blood Stem Cells Healthy as they Age

 – June 10, 2014  –– 

A protein may be the key to maintaining the health of aging blood stem cells, according to work by researchers at the Icahn School of Medicine at Mount Sinai recently published online in Stem Cell Reports. “Our data shows that SIRT1 is a protein that is required to maintain the health of blood stem cells and supports the possibility that reduced function of this protein with age may compromise healthy aging,” said Saghi Ghaffari, MD, PhD, Associate Professor of Developmental and Regenerative Biology at the Black Family Stem Cell Institute of the Icahn School of Medicine at Mount Sinai.

-Dr. Saghi Ghaffari, Associate Professor, Developmental and Regenerative Biology, The Mount Sinai Hospital

-Dr. Pauline Rimmelé, Postdoctoral Fellow, Developmental and Regenerative Biology, The Mount Sinai Hospital

Learn more