Science News - A New Generation of Antidepressants Could Help Patients Feel Better Faster

 – February 1, 2013  –– 

New work from neuroscientists and psychiatrists shows that, in theory, depression can be turned off fast. The drug ketamine and other compounds like it could be prototypes for antidepressants that work in hours instead of weeks. But ketamine is far from the perfect anti¬depressant. Even at low doses, it can cause sensations of floating, separation from physical senses and other hallucinations. Dr. Ming-Hu Han of the Icahn School of Medicine at Mount Sinai says the brain harbors mood wiring that can be turned quickly on or off, and that understanding these sorts of fast switches might help scientists develop drugs that can instantly counteract depression.
-Dr. Ming-Hu Han, Assistant Professor, Phramacology and Systems Therapeutics, Assistant Professor, Neuroscience, Icahn School of Medicine at Mount Sinai
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