"Our department is committed to providing the best neurological care available anywhere in the world, to train the next generation of academic neurologists and researchers, and to pursue cutting-edge biomedical and clinical research that quickly brings even better treatment to our patients."

Stuart C. Sealfon, MD
Sarah B. and Seth M. Glickenhaus Chair Professor and Chair of the Department of Neurology

Stuart C. Sealfon, MD, has directed or co-directed several research and education programs and initiatives at Mount Sinai, including the Pharmacology and Systems Biology Graduate Student Multidisciplinary Training Area, the Center for Genomics, Proteomics, and Bioinformatics, and the Center for Translational Systems Biology. Dr. Sealfon also leads the Modeling Immunity for Biodefense Center/Program for Research on Immune Modeling and Experimentation (PRIME).

A leading systems biologist, Dr. Sealfon's laboratory applies diverse approaches for a better understanding of how drugs work and how cells recognize and generate responses to extracellular signals or stimuli. His research focuses on studying signaling systems, which are critical for understanding cell responses related to Parkinson's disease, drug abuse, viral infection, and neuroendocrine reproductive function.

His work integrates experimental and theoretical approaches, encompasses several areas of brain research and is supported by the National Institute of Drug Abuse, the National Institute of Diabetes, Digestive, and Kidney Diseases, the National Institute of Mental Health, and the National Institute of Allergy and Infectious Disease.

Dr. Sealfon received his AB at Princeton University. After earning his medical degree from Columbia University, Dr. Sealfon completed a residency in neurology at Massachusetts General Hospital. He first joined Mount Sinai as a fellow in neuroscience in 1986.