Laboratories

As a student in our Neuroscience Graduate Training Program, you will devote a significant portion of your time to research. Explore our labs and meet our investigators.

Lab NameDescription
Akbarian Laboratory Laboratory of epigenetic regulation of the human brain
Balchandani Laboratory

Designing radio frequency pulses and pulse sequences via high-field magnets; exploiting new contrast mechanisms for novel MRI applications

Baxter Laboratory Using animal models to establish causal links between manipulations of defined neural circuits, behavioral and cognitive functions
Benson Laboratory Investigating mechanisms required to generate normal functioning neural circuits
Blenkinsop Laboratory Our laboratory works to understand the basic biology of the adult human eye in an effort to reveal mechanisms for regeneration.
Blitzer Laboratory Regulation of translation in long-term potentiation
Brennand Laboratory Studying schizophrenia by reprogramming skin samples into pluripotent stem cells, later differentiated into human neurons
Brezina Laboratory
Focusing on central pattern generating feeding behavior of the mollusc Aplysia, as well as neuromuscular circuits that participate that process 
Buettner Laboratory
Researching glucose and lipid metabolism in liver and adipose tissue
Burdick Laboratory Dr. Burdick’s primary research interest is in neurocognitive dysfunction in major psychiatric disorders with a focus on understanding its underlying etiologies through genetics, neuroimaging, and novel treatment strategies.
Buxbaum Laboratory The laboratory of Molecular Neuropsychiatry studies human psychiatric and neurological diseases using the methods of genetics, genomics, cell and molecular biology and animal models. Current laboratory focus includes autism, schizophrenia and Alzheimer's disease.
Cagan Laboratory
Undertaking a genetic and drug screening approach to target cancer and diabetes, using the Drosophila fruit fly
Cai Laboratory Dr. Cai’s laboratory conducts research studies focusing on the pathogenesis of Alzheimer’s disease.
Casaccia Laboratory Integrating state-of-the-art technologies, animal models, and drug discovery to promote a center of Myelin repair 
Castellano Laboratory Accumulating evidence suggests that both intrinsic and extrinsic factors shape the function of neural circuits within certain substructures of the adult brain
Charney Laboratory  
Chen Laboratory Exploring the use of clinical genome informatics
Chess Laboratory Studying unusual mechanisms involved in regulating gene expression
Clem Laboratory Using molecular and electrophysiological approaches, including optogenetic stimulation, to identify impact of associative fear conditioning on neural pathways and neurons in limbic and cortical regions
Cohen Laboratory Studies in our laboratory are dedicated toward understanding the neural basis for spatial orientation in humans and animals, on Earth and in space.
Cropper Laboratory Studying neural mechanisms of sensorimotor integration
Croxson Laboratory Investigating memory governing networks across different regions of the human brain
Devchand Laboratory  
Devi Laboratory Researching molecular mechanisms in neurology
Dudley Laboratory Focusing on translational and biomedical informatics approaches to address critical challenges in systems medicine
Ehrlich Laboratory  
Elder Laboratory Research interests include Alzheimer's disease and related dementias, in particular how mutations in presenilin-1 cause familial Alzheimer's disease using transgenic mouse models. We also study the normal biological functions of the presenilin-1 gene using mouse models and cell culture.
Ellis-Davies Laboratory Exploring optical methods and neurophysiology
Esplugues Laboratory The main interest of our lab is focused on understanding the cellular and molecular basis that lead to the induction, development and resolution of inflammatory disorders that are caused by the dysfunctions of the innate and/or the adaptive immune system. In particular, we are interested in the study of the TH17 cells, a recently identified CD4+ T cell subset distinct from T helper type 1 (TH1) and T helper type 2 (TH2) cells.
Fromer Laboratory The current focus of Menachem’s research is in developing computational tools to analyze (exome) sequencing data of large samples of thousands of schizophrenia patients in order to uncover genetic variation, in particular structural variation.
Gabbay Laboratory Studying pediatric mood and anxiety disorders
Gandy Laboratory Dr. Gandy is an international expert in the metabolism of the sticky substance called amyloid that clogs the brain in patients with Alzheimer's.
Goate Laboratory Focusing on dementia (Alzheimer's and frontotemporal) and addiction (alcohol)
Goldstein Laboratory Dr. Goldstein is chief of the Brain Imaging Core (BIC) at ISMMS; she also directs the NARC (Neuropsychoimaging of Addiction and Related Conditions) research group that uses multimodality functional neuroimaging methods to explore the neurobiological basis of impaired cognitive and emotional functioning in human drug addiction and other disorders of self-control.
Haghighi Laboratory Investigating epigenetic changes in disease and normal human postmortem brain samples, providing a snapshot of potential abnormalities
Han Laboratory Exploring neurophysiology as it relates to depression and alcoholism
Haroutunian Laboratory Using rodent model systems for Alzheimer’s disease
Hazlett Laboratory Cognitive psychophysiology laboratory
Hof Laboratory Conducting neuromorphology research
Holstein Laboratory Researching chronic liver disease through genomics; clinical diagnostics; chemical biology; biostatistics; and informatics
Huntley Laboratory Researching synaptic circuit development and neural plasticity
Hurd Laboratory Studying the neurobiology of underlying drug abuse and related psychiatric dysfunction
Iyengar Laboratory Exploring how signals are routed and processed through cellular signaling networks, including information sorting and integration mechanisms
John Laboratory Studying multiple sclerosis
Kaplan Laboratory Exploring information processing in the nervous system using the visual system as a model
Kasarskis Laboratory Dr. Kasarskis leads collaborative projects aimed at new therapeutics and diagnostics, and his research focuses on developing and applying technology to several areas including pathogen surveillance, pharmacogenomics, and the genetics of sleep.
Kenny Laboratory Analyzing human genetic variation to address fundamental questions in biology, medicine, and anthropology
Koenigsberg Laboratory Dr. Koenigsberg has had a longstanding research and clinical interest in borderline personality disorder (BPD). He is currently studying the emotional instability characteristic of borderline personality disorder.
Kozlowski Laboratory  
Maze Laboratory Chromatin regulatory mechanisms of neural plasticity and disease
Mlodzik Laboratory Researching the role of aging in obesity, diabetes, and Alzheimer's
Mobbs Laboratory Researching the role of aging in obesity, diabetes, and Alzheimer's 
Montgomery Laboratory Dr. Montgomery’s research focuses on developing, testing and disseminating psychological and integrative interventions to reduce suffering related to cancer and its treatment.
Morishita Laboratory Studying developmental brain plasticity and cognition
Nestler Laboratory Studying molecular mechanisms of addiction and depression
Neves Laboratory Working to decipher the interplay between PDEs and synaptic responsiveness
Paisan-Ruiz Laboratory Dr. Paisan-Ruiz’s laboratory focuses on elucidating and understanding the molecular basis underlying and contributing to movement disorders such as Parkinson's disease (PD), parkinsonian-like syndromes, and essential tremor (ET).
Pasinetti Laboratory Studying biology and treatment of destructive inflammatory mechanisms in the brain, often related to neurodegenerative disorders
Pinto Laboratory Identifying genes and biological pathways involved in various neurodevelopmental disorders
Plevan Laboratory The Plevan laboratory  research interests center around the neurobiology and the neurochemistry of several psychiatric conditions including suicide and drug addiction.
Purcell Laboratory Genetic basis of neuropsychiatric disease
Rich Laboratory Neurophysiology of Affect and Cognition
Robakis Laboratory Laboratory of Molecular Biology and Genetics of Neurodegeneration
Roussos Laboratory Panos Roussos's research is focused on discerning the neurobiology of neuropsychiatric illnesses through understanding the regulation of gene expression.
Rudebeck Laboratory Exploring interactions between the prefrontal cortex and subcortical structures, related to emotional regulation and decision making
Russo Laboratory Researching neuroplasticity and behavior
Salton Laboratory Investigating how neurotrophic growth factors, including nerve growth and brain-derived neurotrophic factors, regulate nervous system development and function
Schadt Laboratory Dr. Schadt is an expert on the generation and integration of very large-scale sequence variation, molecular profiling and clinical data in disease populations for constructing molecular networks that define disease states and link molecular biology to physiology.
Schaefer Laboratory Identifying the epigenetic basis of neurodegenerative and psychiatric disorders
Schiller Laboratory Discovering neural mechanisms underlying emotional control and flexibility
Sealfon Laboratory Using diverse systems biology approaches to study and model the mechanisms of cellular decoding of extracellular stimuli
Shapiro Laboratory Examining the neural mechanisms of memory
Shen Laboratory Performing statistical and integrated analysis of molecular mechanisms of drug addiction and depression
Silverman Laboratory Silverman Laboratory is focused on characterizing phenotypes and endophenotypes in schizophrenia, dementia, successful aging, and autism for use in molecular genetic studies.
Simonyan Laboratory Studying viral replication, especially of retroviruses such as HIV-1, Moloney murine leukemia virus, and XMRV
Sklar Laboratory The laboratory of psychiatric genomics will continue the long-standing basic research program of the PI to define the genetic architecture of the two most severe and heritable adult psychiatric disorders, BD and SCZ.
Slesinger Laboratory Focusing on the function of neural circuits in both normal and diseased states
Sokol Laboratoryy Exploring various processes in epithelial cells; stem cells; migrating cells; asymmetric division; growth factors; and mechanotransduction
Soriano Laboratory Exploring the growth factor signaling pathways that have important roles in mouse embryonic development
Stern Laboratory Exploring the neural basis of cognitive-emotional functioning in healthy individuals and those with obsessive-compulsive and related disorders
Susan Morgello Laboratory Dr. Morgello is the principal investigator of a large, multidisciplinary cohort study/ research resource; examining neurologic, neuropsychologic, psychiatric, neuropathologic, and general medicine abnormalities in HIV.
Tang Laboratory Optimizing and validating novel functional MRI techniques applied to diffuse and focal liver diseases, including diffusion-weighted MRI; dynamic contrast enhanced MRI; MR Elastography; flow quantification; spectroscopy; and multi echo Dixon methods
Wang Laboratory Utilizing biological mass spectrometry to probe protein interactions and processing mechanisms of amyloid beta-protein in Alzheimer's disease
Weiss Laboratory Combining behavioral, morphological, electrophysiological, cell biological and molecular-biological techniques
Wright Laboratory Measures human environment comprehensively including chemicals, air pollution, social stressor and nutrition
Xu Laboratory Developing advanced magnetic resonance techniques to study neurological and psychiatric disorders
Yehuda Laboratory Our programs are designed to gain a better scientific understanding of the biology of stress reactions, and how to treat them better.
Yue Laboratory Studying molecular and cellular mechanisms of neurodegeneration that cause human neurological disorders such as Parkinson’s, Huntington’s and Alzheimer’s diseases
Zachariou Laboratory Using advanced genetic mouse models, viral mediated gene transfer and optogenetics, to understand network and cell-type mechanisms underlying chronic pain, addiction, and depression
Zhang Laboratory Focusing on construction and characterization of multiscale biological networks, from large-scale genomic, genetic, epigenetic, proteomic and clinical data
Zou Laboratory of Axonal Growth and Neuronal Regeneration Researching molecular mechanisms of neuronal birth, extend axons, regeneration or failure to regenerate after mammalian CNS injury

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Application Deadline
December 1