Brian A Kidd, PhD
- ASSISTANT PROFESSOR | Genetics and Genomic Sciences
Research Topics:Bioinformatics, Computational Biology, Immunology, Systems Biology
Brian Kidd, PhD, is an Assistant Professor of Genetics and Genomic Sciences as well as a Member of the Scientific Staff at the Harris Center for Precision Wellness at the Icahn School of Medicine at Mount Sinai.
Dr. Kidd's current research is focused on developing technologies and computational tools to identify biomarkers and molecular signatures of cancer, allergy, autoimmunity, and other immune-mediated conditions. The driving question is how can we best harness the explosion of computing power, information technologies, and publicly available biomedical data, and then integrate these pieces with clinical information to develop predictive models that can solve key issues for the health of individuals and populations. His current research programs are in:
1. Systems immunology and immune monitoring
2. Immune pharmacology
3. Skin health
4. Lyme disease
BS, University of California, San Diego
MS, Stanford University
PhD, University of Washington
Miotto R, Li L, Kidd BA, Dudley JT. Deep Patient: An Unsupervised Representation to Predict the Future of Patients from the Electronic Health Records. Scientific reports 2016; 6.
Kidd BA, Hoffman G, Zimmerman N, Li L, Morgan JW, Glowe PK, Botwin GJ, Parekh S, Babic N, Doust MW, Stock GB, Schadt EE, Dudley JT. Evaluation of direct-to-consumer low-volume lab tests in healthy adults. The Journal of clinical investigation 2016 May; 126(5).
Talukdar HA, Foroughi Asl H, Jain RK, Ermel R, Ruusalepp A, Franzén O, Kidd BA, Readhead B, Giannarelli C, Kovacic JC, Ivert T, Dudley JT, Civelek M, Lusis AJ, Schadt EE, Skogsberg J, Michoel T, Björkegren JL. Cross-Tissue Regulatory Gene Networks in Coronary Artery Disease. Cell systems 2016 Mar; 2(3).
Ruderfer DM, Charney AW, Readhead B, Kidd BA, Kähler AK, Kenny PJ, Keiser MJ, Moran JL, Hultman CM, Scott SA, Sullivan PF, Purcell SM, Dudley JT, Sklar P. Polygenic overlap between schizophrenia risk and antipsychotic response: a genomic medicine approach. The lancet. Psychiatry 2016 Apr; 3(4).
Kidd BA, Wroblewska A, Boland MR, Agudo J, Merad M, Tatonetti NP, Brown BD, Dudley JT. Mapping the effects of drugs on the immune system. Nature biotechnology 2016 Jan; 34(1).
Kidd BA, Readhead BP, Eden C, Parekh S, Dudley JT. Integrative network modeling approaches to personalized cancer medicine. Personalized medicine 2015 Jun; 12(3).
Yu W, Jiang N, Ebert PJ, Kidd BA, Müller S, Lund PJ, Juang J, Adachi K, Tse T, Birnbaum ME, Newell EW, Wilson DM, Grotenbreg GM, Valitutti S, Quake SR, Davis MM. Clonal Deletion Prunes but Does Not Eliminate Self-Specific αβ CD8(+) T Lymphocytes. Immunity 2015 May; 42(5).
Furman D, Jojic V, Sharma S, Shen-Orr SS, Angel CJ, Onengut-Gumuscu S, Kidd BA, Maecker HT, Concannon P, Dekker CL, Thomas PG, Davis MM. Cytomegalovirus infection enhances the immune response to influenza. Science translational medicine 2015 Apr; 7(281).
Kidd BA, Peters LA, Schadt EE, Dudley JT. Unifying immunology with informatics and multiscale biology. Nature immunology 2014 Feb; 15(2).
Newell EW, Sigal N, Nair N, Kidd BA, Greenberg HB, Davis MM. Combinatorial tetramer staining and mass cytometry analysis facilitate T-cell epitope mapping and characterization. Nature biotechnology 2013 Jul; 31(7).
Furman D, Jojic V, Kidd B, Shen-Orr S, Price J, Jarrell J, Tse T, Huang H, Lund P, Maecker HT, Utz PJ, Dekker CL, Koller D, Davis MM. Apoptosis and other immune biomarkers predict influenza vaccine responsiveness. Molecular systems biology 2013; 9.
Su LF, Kidd BA, Han A, Kotzin JJ, Davis MM. Virus-specific CD4(+) memory-phenotype T cells are abundant in unexposed adults. Immunity 2013 Feb; 38(2).