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Charles Powell

  • PROFESSOR Medicine, Pulmonary, Critical Care and Sleep Medicine
  • CHIEF EXECUTIVE OFFICER MOUNT SINAI-NATIONAL JEWISH HEALTH RESPIRATORY INSTITUTE
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Certifications

  • Critical Care Medicine

  • Pulmonary Disease

  • American Board of Internal Medicine

Education

  • MD, University of Chicago

  • Residency, Internal Medicine
    Columbia-Presbyterian Medical Center

  • Fellowship, Pulmonary, Crit Care
    Boston University

Biography

    IN THE NEWS: Dr. Powell discusses the risk factors for lung cancer in the The Daily News feature, The Daily Checkup

Publications

Powell CA, Spira A, Derti A, DeLisi C, Liu G, Borczuk A, Busch S, Sahasrabudhe S, Chen Y, Sugarbaker D, Bueno R, Richards WG, Brody JS. Gene expression in lung adenocarcinomas of smokers and nonsmokers. American journal of respiratory cell and molecular biology 2003 Aug; 29(2).

Borczuk AC, Gorenstein L, Walter KL, Assaad AA, Wang L, Powell CA. Non-small-cell lung cancer molecular signatures recapitulate lung developmental pathways. The American journal of pathology 2003 Nov; 163(5).

Borczuk AC, Shah L, Pearson GD, Walter KL, Wang L, Austin JH, Friedman RA, Powell CA. Molecular signatures in biopsy specimens of lung cancer. American journal of respiratory and critical care medicine 2004 Jul; 170(2).

Borczuk AC, Kim HK, Yegen HA, Friedman RA, Powell CA. Lung adenocarcinoma global profiling identifies type II transforming growth factor-beta receptor as a repressor of invasiveness. American journal of respiratory and critical care medicine 2005 Sep; 172(6).

Borczuk AC, Cappellini GC, Kim HK, Hesdorffer M, Taub RN, Powell CA. Molecular profiling of malignant peritoneal mesothelioma identifies the ubiquitin-proteasome pathway as a therapeutic target in poor prognosis tumors. Oncogene 2007 Jan; 26(4).

Borczuk AC, Powell CA. Expression profiling and lung cancer development. Proceedings of the American Thoracic Society 2007 Jan; 4(1).

Borczuk AC, Papanikolaou N, Toonkel RL, Sole M, Gorenstein LA, Ginsburg ME, Sonett JR, Friedman RA, Powell CA. Lung adenocarcinoma invasion in TGFbetaRII-deficient cells is mediated by CCL5/RANTES. Oncogene 2008 Jan; 27(4).

Borczuk AC, Qian F, Kazeros A, Eleazar J, Assaad A, Sonett JR, Ginsburg M, Gorenstein L, Powell CA. Invasive size is an independent predictor of survival in pulmonary adenocarcinoma. The American journal of surgical pathology 2009 Mar; 33(3).

Borczuk AC, Toonkel RL, Powell CA. Genomics of lung cancer. Proceedings of the American Thoracic Society 2009 Apr; 6(2).

Lee MC, Boroczky L, Sungur-Stasik K, Cann AD, Borczuk AC, Kawut SM, Powell CA. Computer-aided diagnosis of pulmonary nodules using a two-step approach for feature selection and classifier ensemble construction. Artificial intelligence in medicine 2010 Sep; 50(1).

Cheng H, Xu X, Costa DB, Powell CA, Halmos B. Molecular testing in lung cancer: the time is now. Current oncology reports 2010 Sep; 12(5).

Travis WD, Rekhtman N, Riley GJ, Geisinger KR, Asamura H, Brambilla E, Garg K, Hirsch FR, Noguchi M, Powell CA, Rusch VW, Scagliotti G, Yatabe Y. Pathologic diagnosis of advanced lung cancer based on small biopsies and cytology: a paradigm shift. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2010 Apr; 5(4).

Toonkel RL, Borczuk AC, Powell CA. Tgf-beta signaling pathway in lung adenocarcinoma invasion. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2010 Feb; 5(2).

Wilgus ML, Borczuk AC, Stoopler M, Ginsburg M, Gorenstein L, Sonett JR, Powell CA. Lysyl oxidase: A lung adenocarcinoma biomarker of invasion and survival. Cancer 2010 Nov;.

Travis WD, Brambilla E, Noguchi M, Nicholson AG, Geisinger KR, Yatabe Y, Beer DG, Powell CA, Riely GJ, Van Schil PE, Garg K, Austin JH, Asamura H, Rusch VW, Hirsch FR, Scagliotti G, Mitsudomi T, Huber RM, Ishikawa Y, Jett J, Sanchez-Cespedes M, Sculier JP, Takahashi T, Tsuboi M, Vansteenkiste J, Wistuba I, Yang PC, Aberle D, Brambilla C, Flieder D, Franklin W, Gazdar A, Gould M, Hasleton P, Henderson D, Johnson B, Johnson D, Kerr K, Kuriyama K, Lee JS, Miller VA, Petersen I, Roggli V, Rosell R, Saijo N, Thunnissen E, Tsao M, Yankelewitz D. International association for the study of lung cancer/american thoracic society/european respiratory society international multidisciplinary classification of lung adenocarcinoma. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2011 Feb; 6(2).

Industry Relationships

Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device and biotechnology companies to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their relationships with such companies.

Below are financial relationships with industry reported by Dr. Powell during 2012 and/or 2013. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.

Consulting:

  • Pfizer Inc.

Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website at http://icahn.mssm.edu/about-us/services-and-resources/faculty-resources/handbooks-and-policies/faculty-handbook. Patients may wish to ask their physician about the activities they perform for companies.

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