Our group's major interests were in the field of Inborn Errors of Metabolism mainly involving but not restricted to the following conditions: PKU and Maternal PKU, Tetrahydrobiopterin deficiency, MSUD,  Homocystinemia, Tyrosinemia, The Urea Cycle Enzymes deficiencies, The Organic acidemias as MMA, PA, Isovaleric acidemia, Glutaric acidemia type I and II and including primary Lactic acidosis, Primary Hypoglycemia, Galactosemia, HFI, GSD; Carnitine deficiency, The Fatty acid Oxidation defects, The Mitochondrial disorders, The Lysosomal disorders and others.  The research impetus was on the evaluation and development of new diagnosis approaches and novel therapies for these conditions. Some representative themes can be found in the following articles. Emphasis was also placed on teaching.