- ASSISTANT PROFESSOR Pharmacology and Systems Therapeutics
B.E., Stony Brook University
M.S., Stony Brook University
Ph.D., Columbia University
- Dr. Azeloglu is an Assistant Professor in the Department of Pharmacology and Systems Therapeutics. He received his B.E. in Mechanical Engineering and M.S. in Biomedical Engineering from State University of New York at Stony Brook. He completed his Ph.D. in Biomedical Engineering from Columbia University in the City of New York and a postdoctoral fellowship in Department of Pharmacology and Systems Therapeutics in Icahn School of Medicine at Mount Sinai. He was awarded the Yuen-huo Hung & Chao-chin Huang Award from Columbia University and a Howard Hughes Medical Institute fellowship from the Life Science Research Foundation. His research focuses on cell and tissue biomechanics, cardiovascular mechanobiology, systems biology and tissue engineering.
2010 - 2013
Howard Hughes Medical Institute Fellowship
Life Science Research Foundation
Yuen-huo Hung & Chao-chin Huang Award (2009)
2005 - 2007
Stony Wold Herbert Fellowship
ResearchOur main goal at the Systems Bioengineering Lab is to understand cellular decision-making capabilities related to biomechanical and electrochemical signal processing. We employ multiscale experimental and computational techniques as well as microfabrication and tissue engineering methods to study cell signaling, biomechanics, tissue function and regeneration using cardiovascular and renal model systems. We also use multi-platform omics technologies and network analyses for identification of key information processing hubs and regulatory motifs that can be used as therapeutic targets in drug development for complex diseases such as hypertension, heart failure and diabetic nephropathy. See Azeloglu Lab website for more details.
Azeloglu EU, Hardy SV, Eungdamrong NJ, Chen Y, Jayaraman G, Chuang PY, Fang W, Xiong H, Neves SR, Jain MR, Li H, Ma'ayan A, Gordon RE, He JC, Iyengar R. Interconnected network motifs control podocyte morphology and kidney function. Science signaling 2014 Feb; 7(311).
Zhao S, Nishimura T, Chen Y, Azeloglu EU, Gottesman O, Giannarelli C, Zafar MU, Benard L, Badimon JJ, Hajjar RJ, Goldfarb J, Iyengar R. Systems pharmacology of adverse event mitigation by drug combinations. Science translational medicine 2013 Oct; 5(206).
Rangamani P, Lipshtat A, Azeloglu EU, Calizo RC, Hu M, Ghassemi S, Hone J, Scarlata S, Neves SR, Iyengar R. Decoding information in cell shape. Cell 2013 Sep; 154(6).
Azeloglu EU, Costa KD. Atomic force microscopy in mechanobiology: measuring microelastic heterogeneity of living cells. Methods in molecular biology (Clifton, N.J.) 2011; 736.
Azeloglu EU, Costa KD. Cross-bridge cycling gives rise to spatiotemporal heterogeneity of dynamic subcellular mechanics in cardiac myocytes probed with atomic force microscopy. American journal of physiology. Heart and circulatory physiology 2010 Mar; 298(3).
Azeloglu EU, Albro MB, Thimmappa VA, Ateshian GA, Costa KD. Heterogeneous transmural proteoglycan distribution provides a mechanism for regulating residual stresses in the aorta. American journal of physiology. Heart and circulatory physiology 2008 Mar; 294(3).
Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device and biotechnology companies to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their relationships with such companies.
Dr. Azeloglu did not report having any of the following types of financial relationships with industry during 2015 and/or 2016: consulting, scientific advisory board, industry-sponsored lectures, service on Board of Directors, participation on industry-sponsored committees, equity ownership valued at greater than 5% of a publicly traded company or any value in a privately held company. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.
Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.
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