Photo of Fatima A. Sehba

Fatima A. Sehba

  • ASSOCIATE PROFESSOR Neurosurgery
  • ASSOCIATE PROFESSOR Neuroscience
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Education

  • M.S., College of Pharmacy and Allied Health Professions, St. John's University
    Pharmaceutical Sciences

  • B.S., University of Karachi
    Pharmacy

  • PhD, College of Pharmacy and Allied Health Professions, St. John's University
    Pharmaceutical Sciences

Biography

    Dr. Sehba came to Mount Sinai in 1997 as a Postdoctoral Research Fellow in the Cerebrovascular Research Laboratory of Neurosurgery, and in 2001 she was promoted to Assistant Professor. She has a joint appointment in the Department of Neurosciences. Dr. Sehba is studying early cerebral injury after subarachnoid hemorrhage. Her research is supported by an RO1 (NIH, NINDS).

Awards

  • 2007 -
    Visiting Professor Grant
    Research Institute of Environmental Research (RIEM) Nagoya University, Japan

Research

Dr. Sehba is studying cerebral injury after subarachnoid hemorrhage, She demonstrated for the first time that anatomical and structural alterations occur in cerebral microvessels early after subarachnoid hemorrhage. Her current research investigates the mechanisms leading to structural alterations and their effect on vessel function.

Publications

Sehba FA, Flores R, Muller A, Friedrich V, Chen JF, Britz GW, Winn HR, Bederson JB. Adenosine A(2A) receptors in early ischemic vascular injury after subarachnoid hemorrhage. J Neurosurg 2009 Nov;: Epub.

Friedrich V, Flores R, Muller A, Sehba FA. . Escape of intraluminal platelets into brain parenchyma after subarachnoid hemorrhage. Neuroscience 2010 Feb; 165(3): 968-975.

Sehba FA, Friedrich, Jr. V, Makonnen G, Bederson JB. Acute cerebral vascular injury occurs after subarachnoid hemorrhage and can be prevented by administration of a Nitric Oxide donor. J Neurosurg 2007; 106(2): 321-329.

Sehba FA, Bederson JB. Mechanisms of acute brain injury after subarachnoid hemorrhage. Neurol Res 2006 Jun; 28(4): 381-98.

Sehba FA, Mostafa G, Friedrich Jr V, Bederson JB. Acute microvascular platelet aggregation after subarachnoid hemorrhage. J Neurosurg 2005 Jun; 102(6): 1094-100.

Sehba FA, Chereshnev I , Maayani S , Bederson JB. Nitric oxide synthase in acute alteration of nitric oxide levels after subarachnoid hemorrhage. Neurosurgery 2004 Sept;.

Sehba FA, Mustafa GA, Knopman JA, Friedrich VA, Bederson JB. Acute alterations in microvascular basal lamina after subarachnoid hemorrhage. JNS 2004 Oct;.

Sehba F, Bederson JB. Mechanisms of injury after acute subarachnoid hemorrhage (SAH). Proceedings of the 17th Spasm Symposium in Osaka 2001; 17(Suppl): 4-23.

Schwartz AY, Masago AA, Sehba FA, Bederson JB. Experimental models of subarachnoid hemorrhage in the rat: A refinement of the endovascular filament model. J. Neuroscience Method 2000; 96: 161-167.

Sehba FA, Schwartz AY, Bederson JB. Decreased nitric oxide availability contributes to acute cerebral ischemia after subarachnoid hemorrhage. Neurosurgery 2000; 47: 208-214.

Sehba FA, Schwartz AY, Chereshnev I , Bederson JB. Acute decrease in cerebral nitric oxide levels after SAH. J. Cerebr Blood F Met 2000; 20: 604-611.

Duttaroy A, Shen J, Shah S , Chen B , Sehba FA, Carroll J , Yoburn BC. Opioid receptor upregulation in -opioid receptor deficient CXBK and outbred Swiss Webster mice. Life Sci 1999; 65: 113-123.

Industry Relationships

Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device and biotechnology companies to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their relationships with such companies.

Dr. Sehba did not report having any of the following types of financial relationships with industry during 2012 and/or 2013: consulting, scientific advisory board, industry-sponsored lectures, service on Board of Directors, participation on industry-sponsored committees, equity ownership valued at greater than 5% of a publicly traded company or any value in a privately held company. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.

Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website at http://icahn.mssm.edu/about-us/services-and-resources/faculty-resources/handbooks-and-policies/faculty-handbook. Patients may wish to ask their physician about the activities they perform for companies.

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