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Jason Bobe

  • SENIOR FACULTY Genetics and Genomic Sciences
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    The focus of my research is prototyping collaborative and participatory models of biomedical research and innovation. I am particularly interested in (a) greatly expanding the rates of participation in organized health research, (b) broadening the types of contributions participants in research are able to make, (c) promoting discovery & innovation through "equal access" and equitable data sharing practices, i.e. those which enable individuals to build highly integrated, longitudinal research profiles with portable, re-usable data and information assets, (d) the creation of well-consented public data resources via the “open consent” framework, (e) building research networks and communities of practice around emerging technologies. Since 2007, I have been working closely with George Church at Harvard to develop the Global Network of Personal Genome Projects (PGP), which includes research studies in 4+ countries that collaborate on the development and evaluation personal genomic technologies and practices at increasing scales. The first site was founded at Harvard Medical School in 2005, followed by sites at Hospital for Sick Kids / University Toronto (2012), University College London (2013), and the Center for Molecular Medicine CeMM in Vienna, Austria (2014). I have co-founded a variety of initiatives, organizations and programs, including:


Ball MP, Thakuria JV, Zaranek AW, Clegg T, Rosenbaum AM, Wu X, Angrist M, Bhak J, Bobe J, Callow MJ, Cano C, Chou MF, Chung WK, Douglas SM, Estep PW, Gore A, Hulick P, Labarga A, Lee JH, Lunshof JE, Kim BC, Kim JI, Li Z, Murray MF, Nilsen GB, Peters BA, Raman AM, Rienhoff HY, Robasky K, Wheeler MT, Vandewege W, Vorhaus DB, Yang JL, Yang L, Aach J, Ashley EA, Drmanac R, Kim SJ, Li JB, Peshkin L, Seidman CE, Seo JS, Zhang K, Rehm HL, Church GM. A public resource facilitating clinical use of genomes. Proceedings of the National Academy of Sciences of the United States of America 2012 Jul; 109(30).

Lunshof JE, Bobe J, Aach J, Angrist M, Thakuria JV, Vorhaus DB, Hoehe MR, Church GM. Personal genomes in progress: from the human genome project to the personal genome project. Dialogues in clinical neuroscience 2010; 12(1).

Bobe JR. To the moon: In support of the genomic astronauts who will take us there. [editorial]. Genomics Law Report 2009;(Fall).

Industry Relationships

Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device and biotechnology companies to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their relationships with such companies.

Dr. Bobe did not report having any of the following types of financial relationships with industry during 2013 and/or 2014: consulting, scientific advisory board, industry-sponsored lectures, service on Board of Directors, participation on industry-sponsored committees, equity ownership valued at greater than 5% of a publicly traded company or any value in a privately held company. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.

Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website at Patients may wish to ask their physician about the activities they perform for companies.

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