Research Topics
Training Areas
Education
Ph.D., New York University
Clinical PsychologyB.A., Oberlin College
M.A., New York University
Clinical Psychology
Research
Specific Clinical/Research Interest: My group is especially focused on characterizing phenotypes and endophenotypes in schizophrenia, dementia, successful aging, and autism for use in molecular genetic studies.
Postdoctoral Fellows: Esther Vierck, Ph.D.
Research Personnel: Michal Schnaider Beeri, Ph.D.; Jose Carrion-Baralt, Ph.D.; Irina Bespalova, Ph.D.
Dr. Jeremy M. Silverman is a Professor in the Department of Psychiatry at the Mount Sinai School of Medicine and the Director of the Mount Sinai Family Studies Research Center which he established in 1988. He received his B.A. from Oberlin College (1978) and his Ph.D. in clinical psychology from New York University (1987). He joined the Psychiatry Department faculty at Mount Sinai in 1987. Dr. Silverman's major research interests pertain to the genetics of psychiatric disorders and, more specifically, the improved delineation of phenotypes and endophenotypes (intermediate phenotypes) associated with schizophrenia, autism, Alzheimer's disease, and successful cognitive aging in order to strengthen gene finding strategies. Dr. Silverman is also interested in the identification of non-genetic risk and protective factors associated with these conditions.
Publications
Smith CJ, Lang CM, Kryzak L, Reichenberg A, Hollander E, Silverman JM. Familial Associations of Intense Preoccupations, an Empirical Factor of the Restricted, Repetitive Behaviors and Interests Domain of Autism. Journal of Child Psychology and Psychiatry;: in press.
Silverman JM, Schnaider Beeri M, Schmeidler J, Grossman H, Mavris R, Rosendorff C, West R, Hannigan C. C-reactive protein, cognitive performance, and APOE suggest antagonistic pleiotropy in very elderly nondemented subjects. Age and Ageing ;: in press.
Schnaider Beeri M, Schmeidler J, Silverman JM, Gandy SE, Wysocki M, Hannigan CM, Purohit DP, Lesser G, Grossman HT, Haroutunian V. Insulin together with other diabetes medication is associated with less Alzheimer neuropathology. Neurology 2008; 71: 750-757.
West R, Schnaider Beeri M, Schmeidler J, Hannigan C, Angelo G, Rosendorff C, Silverman JM. Better memory functioning associated with higher total and LDL cholesterol levels in very elderly subjects without the APOE4 allele. Am J Geriatric Psychiatry 2008; 16: 781-785.
Puleo CM, Reichenberg A, Smith CJ, Kryzak LA, Silverman JM. Do autism related personality traits explain higher paternal age in autism?. Molecular Psychiatry 2008; 13: 243-244.
Silverman JM, Buxbaum JD, Ramoz N, Schmeidler J, Reichenberg A, Hollander E, Angelo G, Smith CJ, Kryzak LA. Autism Related Routines and Rituals Associated with a Mitochondrial Aspartate/Glutamate Carrier SLC25A12 Polymorphism. Am J Medical Genetics (Neuropsychiatric Genetics) 2008; 147: 408-410.
Silverman JM, Schnaider-Beeri M, Grossman HT, Schmeidler J, Wang JY, Lally RC. A phenotype for genetic studies of successful cognitive aging. Am J Med Genet B Neuropsychiatr Genet 2008; 147B: 167-173.
Greenwood TA, Braff DL, Cadenhead KS, Calkins ME, Dobie DJ, Freedman R, Green MF, Gur RE, Gur RC, Light GA, Mintz J, Nuechterlein KH, Olincy A, Radant AD, Seidman LJ, Siever LJ, Silverman JM, Stone WS, Swerdlow NR, Tsuang DW, Tsuang MT, Turetsky BI, Schork NJ. The Consortium on the Genetics of Schizophrenia (COGS): Initial Heritability Analyses of Endophenotypic Measures for Schizophrenia. Archives of General Psychiatry 2007; 33: 33-48.
Kolevzon A, Weiser M, Gross R, Lubin G, Knobler HY, Schmeidler J, Silverman JM, Reichenberg A. Season of birth effects in autism spectrum disorders: fact or fiction?. Am J Psychiatry 2006; 163: 1288-1290.
Bespalova IN, Angelo G, Smith CJ, Durner M, Siever LJ, Buxbaum JD, Silverman JM. Fine mapping of the 5p13 locus linked to schizophrenia and schizotypal disorder in a Puerto Rican family. Psychiatric Genetics 2005;: 205-210.
Clinical Trials
Industry Relationships
Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device and biotechnology companies to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their relationships with such companies.
Dr. Silverman did not report having any of the following types of financial relationships with industry during 2012 and/or 2013: consulting, scientific advisory board, industry-sponsored lectures, service on Board of Directors, participation on industry-sponsored committees, equity ownership valued at greater than 5% of a publicly traded company or any value in a privately held company. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.
Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website at http://icahn.mssm.edu/about-us/services-and-resources/faculty-resources/handbooks-and-policies/faculty-handbook. Patients may wish to ask their physician about the activities they perform for companies.
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