Photo of Jianzhong Hu

Jianzhong Hu

  • ASSISTANT PROFESSOR Genetics and Genomic Sciences
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Education

  • MS, Baruch College, CUNY
    Statistics

  • PhD, Graduate Center, CUNY
    Biochemistry

Publications

Hu J, Nudelman G, Shimoni Y, Kumar M, Ding Y, López C, Hayot F, Wetmur JG, Sealfon SC. Role of Cell-to-Cell Variability in Activating a Positive Feedback Antiviral Response in Human Dendritic Cells. PloS one 2011; 6(2).

Hu J, Nistal-Villán E, Voho A, Ganee A, Kumar M, Ding Y, García-Sastre A, Wetmur JG. A common polymorphism in the caspase recruitment domain of RIG-I modifies the innate immune response of human dendritic cells. Journal of immunology (Baltimore, Md. : 1950) 2010 Jul; 185(1).

Nudelman G, Ge Y, Hu J, Kumar M, Seto J, Duke JL, Kleinstein SH, Hayot F, Sealfon SC, Wetmur JG. Coregulation mapping based on individual phenotypic variation in response to virus infection. Immunome research 2010; 6.

Diplas AI, Hu J, Lee MJ, Ma YY, Lee YL, Lambertini L, Chen J, Wetmur JG. Demonstration of all-or-none loss of imprinting in mRNA expression in single cells. Nucleic acids research 2009 Nov; 37(21).

Hu J, Iyer-Biswas S, Sealfon SC, Wetmur J, Jayaprakash C, Hayot F. Power-laws in interferon-B mRNA distribution in virus-infected dendritic cells. Biophysical journal 2009 Oct; 97(7).

Hu J, Sealfon SC, Hayot F, Jayaprakash C, Kumar M, Pendleton AC, Ganee A, Fernandez-Sesma A, Moran TM, Wetmur JG. Chromosome-specific and noisy IFNB1 transcription in individual virus-infected human primary dendritic cells. Nucleic acids research 2007; 35(15).

Banerjee A, Hu J, Goss DJ. Thermodynamics of protein-protein interactions of cMyc, Max, and Mad: effect of polyions on protein dimerization. Biochemistry 2006 Feb; 45(7).

Hu J, Banerjee A, Goss DJ. Assembly of b/HLH/z proteins c-Myc, Max, and Mad1 with cognate DNA: importance of protein-protein and protein-DNA interactions. Biochemistry 2005 Sep; 44(35).

Scheper GC, van Kollenburg B, Hu J, Luo Y, Goss DJ, Proud CG. Phosphorylation of eukaryotic initiation factor 4E markedly reduces its affinity for capped mRNA. The Journal of biological chemistry 2002 Feb; 277(5).

Industry Relationships

Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device and biotechnology companies to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their relationships with such companies.

Dr. Hu did not report having any of the following types of financial relationships with industry during 2012 and/or 2013: consulting, scientific advisory board, industry-sponsored lectures, service on Board of Directors, participation on industry-sponsored committees, equity ownership valued at greater than 5% of a publicly traded company or any value in a privately held company. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.

Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website at http://icahn.mssm.edu/about-us/services-and-resources/faculty-resources/handbooks-and-policies/faculty-handbook. Patients may wish to ask their physician about the activities they perform for companies.

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