Mount Sinai Logo

John Mascarenhas

  • ASSOCIATE PROFESSOR Medicine, Hematology and Medical Oncology
Print ProfilePrint Profile


  • Medical Oncology

  • Hematology


  • American Board of Internal Medicine


  • MD, New York Medical College

  • Residency, Internal Medicine
    Rhode Island Hospital

  • Fellowship, Hematology
    Mount Sinai Hospital


    Dr. John Mascarenhas is a clinical investigator in malignant hematology with a focus in translational research involving the Myeloproliferative Neoplasms. Dr. Mascarenhas is primarily responsible for the clinical trials arm of the Mount Sinai School of Medicine Myeloproliferative Disorders Program headed by Dr. Ronald Hoffman. This program offers phase I/II and III studies for patients with myelofibrosis, polycythemia vera, essential thrombocythemia, chronic myelogenous leukemia, and forms of acute myeloid leukemia. In addition, Dr. Mascarenhas treats patients with myelodysplastic syndrome, hypereosinophilic syndrome, systemic mastocytosis, chronic myelomonocytic leukemia and related issues.

    Clinical trials:
    • A Phase I/II Open Label Study of LBH589, a Novel Histone Deacetylase Inhibitor (HDACi), in Patients with Primary Myelofibrosis (PMF) and Post-Polycythemia/Essential Thrombocythemia Myelofibrosis (Post-PV/ET MF)
    • A Phase I/II, Open Label Multi-Centre Study to Assess the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of the JAK2 inhibitor AZD1480 Administered Orally to Patients with Primary Myelofibrosis (PMF) and Post-Polycythaemia Vera/Essential Thrombocythaemia Myelofibrosis (Post-PV/ET MF)
    • Phase I study of GC1008 in patients with primary myelofibrosis (PMF), post-polycythemia vera/essential thrombocythemia related myelofibrosis (post-PV/ET MF) and essential thrombocythemia (ET)

    In this episode of "Healthy Body, Healthy Mind" Dr. Mascarenhas discusses myelofibrosis - including why it's an unfamiliar term for many people, the rarity of the disease, and the age at which most people are diagnosed.


  • 2010 - 2010
    Richard E. Rosenfeld Faculty Achievement Award


Mascarenhas J, Navada S, Malone A, Rodriguez A, Najfeld V, Hoffman R. Therapeutic options for patients with myelofibrosis in blast phase. Leukemia Research 2010 June; 34(9): 1246-1249.

Clinical Trials

Industry Relationships

Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device and biotechnology companies to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their relationships with such companies.

Below are financial relationships with industry reported by Dr. Mascarenhas during 2015 and/or 2016. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.

Other Activities: Examples include, but are not limited to, committee participation, data safety monitoring board (DSMB) membership.

  • Incyte Corporation; Novartis

Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.

Insurance Information

Physicians who provide services at hospitals and facilities in the Mount Sinai Health System might not participate in the same health plans as those Mount Sinai hospitals and facilities (even if the physicians are employed or contracted by those hospitals or facilities).

Information regarding insurance participation and billing by this physician may be found on this page, and can also be obtained by contacting this provider directly. Because physicians insurance participation can change, the insurance information on this page may not always be up-to-date. Please contact this physician directly to obtain the most up-to-date insurance information.

Insurance and health plan networks that the various Mount Sinai Health System hospitals and facilities participate in can be found on the Mount Sinai Health System website.

Edit profile in Sinai Central


Annenberg Building Floor Atran E Room ABE-09
1468 Madison Avenue
New York, NY 10029

Tel: 212-241-3417
Fax: 212-876-5276
Ruttenberg Treatment Center

1470 Madison Avenue
3rd floor
New York, NY 10029

Tel: 212-241-6756
Fax: 212-876-5276
Get Directions
  • Spanish
Insurance Plans
  • 1199
  • Access Medicare
  • Aetna
  • Affinity
  • Amerigroup
  • AmidaCare
  • Cigna - HMO
  • Empire Blue Cross/Blue Shield - PPO
  • Fidelis Medicare
  • GHI
  • Health Insurance Plan (HIP) - HMO
  • Healthfirst
  • Humana
  • Island Group
  • Magnacare
  • Medicaid of New York
  • Medicare
  • MetroPlus Health Plan
  • MultiPlan, Inc.
  • Oxford Health Plans
  • Pomco
  • United Healthcare
  • VNS Medicare
  • WellCare of New York, Inc.
Payment Methods
  • Master Card
  • Visa
  • American Express
  • Discover
  • Personal Check
  • Cash
  • Credit Card (Other)