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Kiastoutis Planoutis

  • ASSISTANT PROFESSOR Medicine, Hematology and Medical Oncology
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Research

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We work with Wnt pathway that is important in developmental processes and stem cell regulation in healthy organisms. The list of Wnt pathway targets includes cellular growth controling genes (e.g. cyclinD1), genes for invasion (like metalloproteinases) and angiogenesis (for example vascular endothelial growth factor) sustaining genes. The presence of such diverse set of genes among the targets shows that Wnt pathway is involved not only in the cellular growth regulation. Wnts participate also in the tumor invasion control and the tumor blood vessel formation. We study Wnt-dependent regulation of these mortality causing processes in a major disease - colon cancer.

Industry Relationships

Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device and biotechnology companies to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their relationships with such companies.

Dr. Planoutis did not report having any of the following types of financial relationships with industry during 2012 and/or 2013: consulting, scientific advisory board, industry-sponsored lectures, service on Board of Directors, participation on industry-sponsored committees, equity ownership valued at greater than 5% of a publicly traded company or any value in a privately held company. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.

Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website at http://icahn.mssm.edu/about-us/services-and-resources/faculty-resources/handbooks-and-policies/faculty-handbook. Patients may wish to ask their physician about the activities they perform for companies.

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