Mount Sinai Logo

Mary Jane Potash

  • ASSOCIATE PROFESSOR Medicine, Infectious Diseases
  • ASSOCIATE PROFESSOR Pathology
Print ProfilePrint Profile

Biography

    Mary Jane Potash obtained her AB from Wellesley College and her PhD from Brown University. She trained at the Basel Institute of Immunology and served on the faculty of Harvard Medical School and Columbia University Medical Center before the merger between Mt Sinai and St. Luke's-Roosevelt Hospital. Since 1988 her research has focused on HIV replication and control.

Awards

  • 1987 -
    Staff Award, Institute of Medicine, National Academy of Sciences

Publications

Potash MJ, Knopf PM. Differential sensitivity of memory cell subpopulations to anti-immunoglobulin and complement. European journal of immunology 1978 Oct; 8(10).

Potash MJ. B lymphocyte stimulation. Cell 1981 Jan; 23(1).

Köhler G, Potash MJ, Lehrach H, Shulman MJ. Deletions in immunoglobulin mu chains. The EMBO journal 1982; 1(5).

Sidman C, Potash MJ, Köhler G. Roles of protein and carbohydrate in glycoprotein processing and secretion. Studies using mutants expressing altered IgM mu chains. The Journal of biological chemistry 1981 Dec; 256(24).

Leptin M, Potash MJ, Grützmann R, Heusser C, Shulman M, Köhler G, Melchers F. Monoclonal antibodies specific for murine IgM I. Characterization of antigenic determinants on the four constant domains of the mu heavy chain. European journal of immunology 1984 Jun; 14(6).

Potash MJ, Knopf PM. Cellular subpopulations in the expression of IgG1. Cellular immunology 1979 Dec; 48(2).

Shulman MJ, Hawley RG, Ochi A, Baczynsky WO, Collins C, Pennell N, Potash MJ, Köhler G, Hozumi N. Biochemical genetics of the mouse IgM system. Canadian journal of biochemistry and cell biology = Revue canadienne de biochimie et biologie cellulaire 1984 Apr; 62(4).

Pellegrino MG, Li G, Potash MJ, Volsky DJ. Contribution of multiple rounds of viral entry and reverse transcription to expression of human immunodeficiency virus type 1. A quantitative kinetic study. The Journal of biological chemistry 1991 Jan; 266(3).

Baumann B, Potash MJ, Köhler G. Consequences of frameshift mutations at the immunoglobulin heavy chain locus of the mouse. The EMBO journal 1985 Feb; 4(2).

Hsu MC, Schutt AD, Holly M, Slice LW, Sherman MI, Richman DD, Potash MJ, Volsky DJ. Discovery and characterization of an HIV-1 Tat antagonist. Biochemical Society transactions 1992 May; 20(2).

Potash MJ, Zeira M, Huang ZB, Pearce TE, Eden E, Gendelman HE, Volsky DJ. Virus-cell membrane fusion does not predict efficient infection of alveolar macrophages by human immunodeficiency virus type 1 (HIV-1). Virology 1992 Jun; 188(2).

Volsky DJ, Li G, Hamblet N, Volsky B, Decker RS, Pellegrino MG, Potash MJ. Evaluation of multiple parameters of HIV-1 replication cycle in testing of AIDS drugs in vitro. Antiviral research 1992 Apr; 17(4).

Potash MJ, Bentsman G, McKinley G, Volsky DJ. A Tat antagonist inhibits HIV-1 induction in naturally infected and experimentally infected T cells. Biochemical and biophysical research communications 1992 Nov; 189(1).

Hsu MC, Schutt AD, Holly M, Slice LW, Sherman MI, Richman DD, Potash MJ, Volsky DJ. Inhibition of HIV replication in acute and chronic infections in vitro by a Tat antagonist. Science (New York, N.Y.) 1991 Dec; 254(5039).

Pearce TE, Nowakowski M, Eden E, Huang ZB, Steiner P, Shahabuddin M, Potash MJ, Volsky DJ. Uniform detection of HIV-1 in alveolar macrophages of pediatric but not adult AIDS patients. Journal of leukocyte biology 1993 Jun; 53(6).

Huang ZB, Potash MJ, Simm M, Shahabuddin M, Chao W, Gendelman HE, Eden E, Volsky DJ. Infection of macrophages with lymphotropic human immunodeficiency virus type 1 can be arrested after viral DNA synthesis. Journal of virology 1993 Nov; 67(11).

Hsu MC, Dhingra U, Earley JV, Holly M, Keith D, Nalin CM, Richou AR, Schutt AD, Tam SY, Potash MJ. Inhibition of type 1 human immunodeficiency virus replication by a tat antagonist to which the virus remains sensitive after prolonged exposure in vitro. Proceedings of the National Academy of Sciences of the United States of America 1993 Jul; 90(14).

Li G, Simm M, Potash MJ, Volsky DJ. Human immunodeficiency virus type 1 DNA synthesis, integration, and efficient viral replication in growth-arrested T cells. Journal of virology 1993 Jul; 67(7).

Shahabuddin M, McKinley G, Potash MJ, Volsky DJ. Modulation of cellular gene expression of HIV type 1 infection as determined by subtractive hybridization cloning: downregulation of thymosin beta 4 in vitro and in vivo. AIDS research and human retroviruses 1994 Nov; 10(11).

Flynn TE, Reppucci VS, McKinley G, Potash MJ, Volsky DJ. Detection of HIV-1 in surgical specimens from vitreous of AIDS patients. AIDS (London, England) 1995 Sep; 9(9).

Industry Relationships

Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device and biotechnology companies to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their relationships with such companies.

Dr. Potash did not report having any of the following types of financial relationships with industry during 2014 and/or 2015: consulting, scientific advisory board, industry-sponsored lectures, service on Board of Directors, participation on industry-sponsored committees, equity ownership valued at greater than 5% of a publicly traded company or any value in a privately held company. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.

Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.

Edit profile in Sinai Central