Matthew A Levin

Matthew A Levin, MD

  • ASSOCIATE PROFESSOR | Anesthesiology, Perioperative & Pain Medicine
  • ASSOCIATE PROFESSOR | Genetics and Genomic Sciences



Research Topics:

Bioinformatics, Genomics

Dr. Levin is a Board Certified Cardiac Anesthesiologist, Board Certified Clinical Informaticist, and the Director of Research Informatics in the Department of Anesthesiology.  His research interest lies in leveraging large data sets of intraoperative physiological data to reduce morbidity and mortality and enhance patient safety during the perioperative period.  Over the past several years he has designed and implemented a large perioperative data warehouse containing detailed pre-, post-, and intra-operative information, including high resolution physiological data captured from intraoperative monitoring devices, for over 700,000 surgical cases.  This anesthesia data warehouse continues to grow at a rate of 50,000 cases per year as new case data is automatically added on a real time basis.

Through his multi-disciplinary collaborations with other researchers in the Icahn School of Medicine, Dr. Levin is pushing the boundaries of perioperative research in order to answer previously un-addressable questions on the phenotype and genotype of the response to anesthetic and surgical stress.  Dr. Levin is affiliated with The Charles Bronfman Institute for Personalized Medicine and collaborates closely with fellow IPM member Dr. Eimear Kenny.  Together they were recently awarded a prestigious starter grant from the Society of Cardiovascular Anesthesiologists to investigate the Genomics of Vasoplegia, a condition of profound, persistent hypotension sometimes seen after cardiopulmonary bypass.  Dr. Levin has also been leading an initiatives to build a real-time, streaming data pipeline that uses machine learning to improve the early detection of unexpected deteriorations in clinical status among inpatients and provide real-time alerting to clinicians.
Dr. Levin's 2014 article "Low intraoperative tidal volume ventilation with minimal PEEP is associated with increased mortality" was recently recognized as the most cited article from 2013-2014 in the British Journal of Anaesthesia, contributing to the BJA's increase in impact factor to 5.616.


American Board of Anesthesiology


MD, Mount Sinai School of Medicine

BS, Massachusetts Institute of Technology

Internship, Surgery, Lenox Hill Hospital

Residency, Anesthesiology, Mount Sinai Hospital

Fellowship, Cardiothoracic Anes., Mount Sinai Hospital

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