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Men-Jean Lee

  • ASSOCIATE PROFESSOR (PENDING) Obstetrics, Gynecology and Reproductive Science
  • ASSOCIATE PROFESSOR (PENDING) Preventive Medicine
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Biography

    Men-Jean Lee, MD, is the Director of Perinatal Research in the Department of Obstetrics, Gynecology and Reproductive Science. After receiving a BS from the Honors Program in Medical Education at Northwestern University, Dr. Lee earned her medical degree from the Northwestern University School of Medicine.  After completing her residency in Obstetrics and Gynecology at the McGaw Medical Center Medical Center of Northwestern University, she completed her fellowship training in Maternal-Fetal Medicine at Strong Memorial Hospital, University of Rochester.  Dr. Lee also completed a postdoctoral research fellowship through the Reproductive Scientist Development Program in the Department of Microbiology at the NYU School of Medicine.  Dr. Lee most recently served as the Residency Program Director and Clerkship Director for OB/GYN at the Yale University School of Medicine.  Dr. Lee's special interests include maternal stress during pregnancy, glucocorticoid effects on fetal development, immigrant healthcare, fetal programming and epigenetics, and placental biology.  As a faculty member, Dr. Lee provides prenatal diagnosis and ultrasound services, perinatal consultations, and directs an active perinatal laboratory research program in Maternal-Fetal Medicine.

Research

Research Interests

Placenta biology
Preeclampsia
Intrauterine growth restriction
Fetal programming
Epigenetics
Environment-gene interactions
Maternal stress
Glucocorticoids
Glucocorticoid receptor
Immigrant healthcare
Healthcare disparities

Publications

Dasanayake AP, Chhun N, Tanner AR, Craig RG, Lee MJ, Moore AF, Norman RG. Periodontal Pathogens and Gestational Diabetes Mellitus. J Dent Res 2008; 87(4): 328.

Koklanaris N, Bonanno C, Seubert D, Anzai Y, Jennings R, Lee MJ, . Does raising the glucose challenge test threshold impact birthweight in Asian gravidas?. J Perinat Med 2007; 35(2): 100-103.

Lee MJ, Roman AS, Lusskin S, Chen D, Dulay A, Funai EF, Monteagudo A. Maternal Anxiety and Ultrasound Markers for Aneuploidy in a Multiethnic Population. Prenat Diagn 2007; 27: 40-45.

Koklanaris N, Nwachukwu JC, Huang SJ, Guller S, Karpisheva K, Garabedian M, Lee MJ. First-trimester trophoblast cell model of gene response to hypoxia. Am J Obstet Gynecol 2006; 194(3): 687-693.

Lee MJ, Wang Z, Yee H, Ma Y, Swenson N, Yang L, Kadner SS, Baergen RN, Logan SK, Garabedian MJ, Guller S. Expression and regulation of glucocorticoid receptor in human placental villous fibroblasts. Endocrinology 2005; 146(11): 4619-4626.

Dasanayake AP, Li Y, Wiener H, Ruby JD, Lee MJ. Salivary A. naselundii genospecies 2 and L. casei levels predict pregnancy outcomes. J Periodontology 2005; 76: 171-177.

Lee MJ, Ma Y, LaChapelle L, Kadner SS, Guller S. Glucocorticoid enhances transforming growth factor-{beta} effects on extracellular matrix protein expression in human placental mesenchymal cells. Biol Reprod 2004 May; 70(5): 1246-1252.

Lee MJ, Davies J, Guinn D, Sullivan L, Atkinson MW, McGregor S, Parilla BV, Hanlon-Lundberg K, Simpson L, Stone J, Wing D, Ogasawara K, Muraskas J. Single versus weekly courses of antenatal corticosteroids in preterm premature rupture of membranes. Obstet Gynecol 2004; 103(2): 274-281.

Guinn DA, Atkinson MW, Sullivan L, Lee MJ, MacGregor S, Parilla BV, Davies J, Hanlon-Lundberg K, Simpson L, Stone J, Wing D, Ogasawara K, Muraskas J. Multicenter randomized trial of single versus weekly courses of antenatal corticosteroids (ACS). JAMA 2001; 286(13): 1581-1587.

Industry Relationships

Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device and biotechnology companies to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their relationships with such companies.

Dr.Lee is not currently required to report Industry relationships.

Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website at http://icahn.mssm.edu/about-us/services-and-resources/faculty-resources/handbooks-and-policies/faculty-handbook. Patients may wish to ask their physician about the activities they perform for companies.

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