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Pei Wang

  • SENIOR FACULTY Genetics and Genomic Sciences
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Education

  • BS, Peking University
    Math

  • PhD, Stanford University
    Statistics

Biography

    Dr. Wang received her Ph.D. in Statistics from Stanford University in 2004. Between 2004-2013, she served as a faculty in Fred Hutchinson Cancer Research Center and University of Washington, Seattle, WA. In Oct 2013, Dr. Wang joint Icahn Medical School at Mount Sinai as an Associate Professor of Genetics and Genomics. Dr. Wang’s research work has been focused on developing statistical and computational methods to address scientific questions based on data from high throughput biology/genetics experiments.

Research

High dimensional inference & integrative genomics

I am interested in developing statistical and computational methods to address scientific questions based on data from high throughput biology/genetics experiments. The ultimate goal is to enhance our understanding of cell activities and disease initiation/progression to a system level by integrating information from diverse biological sources (genetics/genomics, proteomics, and phenotypes). Towards this goal, eff orts have been made to properly model each individual type of data and to effectively characterize interactions among different biology molecules. These eff orts all borrow strength from and contribute to the developments of high dimensional inference, a challenging yet thriving field in modern statistics.

Publications

Chen LS, Prentice RL, Wang P. A penalized EM algorithm incorporating missing data mechanism for Gaussian parameter estimation. Biometrics 2014 Jan;.

Hu JK, Wang X, Wang P. Testing gene-gene interactions in genome wide association studies. Genetic epidemiology 2014 Feb; 38(2).

Danaher P, Wang P, Witten DM. The joint graphical lasso for inverse covariance estimation across multiple classes. Journal of the Royal Statistical Society. Series B, Statistical methodology 2014 Mar; 76(2).

Kennedy JJ, Abbatiello SE, Kim K, Yan P, Whiteaker JR, Lin C, Kim JS, Zhang Y, Wang X, Ivey RG, Zhao L, Min H, Lee Y, Yu MH, Yang EG, Lee C, Wang P, Rodriguez H, Kim Y, Carr SA, Paulovich AG. Demonstrating the feasibility of large-scale development of standardized assays to quantify human proteins. Nature methods 2014 Feb; 11(2).

Xu C, Wang P, Liu Y, Zhang Y, Fan W, Upton MP, Lohavanichbutr P, Houck JR, Doody DR, Futran ND, Zhao LP, Schwartz SM, Chen C, Méndez E. Integrative genomics in combination with RNA interference identifies prognostic and functionally relevant gene targets for oral squamous cell carcinoma. PLoS genetics 2013; 9(1).

Lohavanichbutr P, Méndez E, Holsinger FC, Rue TC, Zhang Y, Houck J, Upton MP, Futran N, Schwartz SM, Wang P, Chen C. A 13-gene signature prognostic of HPV-negative OSCC: discovery and external validation. Clinical cancer research : an official journal of the American Association for Cancer Research 2013 Mar; 19(5).

Li S, Hsu L, Peng J, Wang P. BOOTSTRAP INFERENCE FOR NETWORK CONSTRUCTION WITH AN APPLICATION TO A BREAST CANCER MICROARRAY STUDY. The annals of applied statistics 2013 Mar; 7(1).

Wang X, Li Q, Zhang H, Zhang Y, Li H, Wang P. A regularized multivariate regression approach for eQTL analysis. Statistics in Biosciences 2013 Nov; 10.1007/s12561-013-9106-9.

Industry Relationships

Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device and biotechnology companies to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their relationships with such companies.

Dr. Wang did not report having any of the following types of financial relationships with industry during 2013 and/or 2014: consulting, scientific advisory board, industry-sponsored lectures, service on Board of Directors, participation on industry-sponsored committees, equity ownership valued at greater than 5% of a publicly traded company or any value in a privately held company. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.

Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website at http://icahn.mssm.edu/about-us/services-and-resources/faculty-resources/handbooks-and-policies/faculty-handbook. Patients may wish to ask their physician about the activities they perform for companies.

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