Priti Balchandani, PhD
- ASSOCIATE PROFESSOR | Radiology
- ASSOCIATE PROFESSOR | Neuroscience
Research Topics:Biomechanics/Bioengineering, Brain, Brain Imaging, Epilepsy, Imaging, MRI, Magnetic Resonance Imaging, Mathematical Modeling of Biomedical Systems, Neuroscience
Priti Balchandani, PhD, is an Assistant Professor of Radiology and Director of the High Field MRI Program at the Translational and Molecular Imaging Institute at Mount Sinai School of Medicine. Her research is focused on novel RF pulse and pulse sequence design for human MR imaging and spectroscopy. She has been particularly interested in exploiting the power of high-field MR magnets to visualize the brain in unprecedented detail. Her work on overcoming some of the main limitations of operating at high magnetic fields has resulted in several U.S. patents as well as selection as a finalist for the International Society for Magnetic Resonance in Medicine (ISMRM) 2008 Young Investigator Award. Dr. Balchandani is the recipient of a K99/R00 NIH Pathway to Independence Award from the National Institute of Neurological Disorders and Stroke for her grant entitled "High Resolution Magnetic Resonance Imaging and Spectroscopy of Epilepsy at 7T." She was also named a Junior Fellow of the ISMRM. Prior to her work in medical imaging, Dr. Balchandani developed ultraprecise measurement instrumentation for the Gravity Probe-B group, a team of scientists at Stanford University who sent a satellite into earth orbit to test two predictions of Einstein’s Theory of General Relativity. Dr. Balchandani received her BASc in computer engineering at the University of Waterloo in Canada and her PhD in electrical engineering at Stanford University.
Multi-Disciplinary Training AreasBiophysics and Systems Pharmacology [BSP], Neuroscience [NEU]
BASc, University of Waterloo
MS, Stanford University
PhD, Stanford University
NIH Pathway to Independence Award
Named Junior Fellow of International Society for Magnetic Resonance in Medicine (ISMRM)
Young Investigators’ Award Finalist at ISMRM
Novel MRI techniques to visualize the brain
Dr. Balchandani’s primary research goal is to develop anatomic, spectroscopic and functional magnetic resonance (MR) imaging tools to elucidate changes in brain structure, metabolism and function in the presence of disease. Her work is focused on the application of signal processing principles to the development of novel radio frequency (RF) pulses and pulse sequences that maximize the information imparted by MR images. She has developed several techniques to harness the power of high-field MR magnets by overcoming physical and hardware limitations in order to visualize the human brain in unprecedented structural and metabolic detail. In addition, she is interested in obtaining a direct window into neuronal activation and function by improving current functional imaging techniques and exploiting the MR signal of nuclei other than hydrogen. Together, these techniques have the potential to drastically improve diagnosis, treatment and monitoring of neurological diseases and disorders as well as advance our understanding of the brain in the normal state.
Balchandani P, Glover G, Pauly J, Spielman D. Improved slice-selective adiabatic excitation. Magnetic resonance in medicine;.
Balchandani P, Khalighi MM, Glover G, Pauly J, Spielman D. Self-refocused adiabatic pulse for spin echo imaging at 7 T. Magnetic resonance in medicine 2012 Apr; 67(4).
Balchandani P, Pauly J, Spielman D. Designing adiabatic radio frequency pulses using the Shinnar-Le Roux algorithm. Magnetic resonance in medicine 2010 Sep; 64(3).
Balchandani P, Yamada M, Pauly J, Yang P, Spielman D. Self-refocused spatial-spectral pulse for positive contrast imaging of cells labeled with SPIO nanoparticles. Magnetic resonance in medicine 2009 Jul; 62(1).
Balchandani P, Spielman D. Fat suppression for 1H MRSI at 7T using spectrally selective adiabatic inversion recovery. Magnetic resonance in medicine 2008 May; 59(5).
Balchandani P, Pauly J, Spielman D. Slice-selective tunable-flip adiabatic low peak-power excitation pulse. Magnetic resonance in medicine 2008 May; 59(5).
Balchandani P, Pauly J, Spielman D. Interleaved narrow-band PRESS sequence with adiabatic spatial-spectral refocusing pulses for 1H MRSI at 7T. Magnetic resonance in medicine 2008 May; 59(5).
Balchandani P, Torii R, Shile R. Thin-film persistent current switch. IEEE Trans. Appl. Supercond. 2005 Sep; 15(3).
Balchandani P, Qiu D. Semi-adiabatic Shinnar-Le Roux pulses and their application to diffusion tensor imaging of humans at 7T. Magnetic resonance imaging 2014 Sep; 32(7).
Balchandani P, Naidich TP. Ultrahigh Field Magnetic Resonance Neuroimaging [review]. American Journal of Neuroradiology;.