Randy A Albrecht, PhD
- ASSOCIATE PROFESSOR | Microbiology
Research Topics:Antivirals, Autophagy, Biodefense, Cellular Immunity, Cytokines, Epithelial Cells, Gene Expressions, Gene Regulation, Immune Antagonism, Infectious Disease, Influenza Virus, Interferon, Interferon Antagonists, Lung, Molecular Biology, Mucosal Immunology, Protein Structure/Function, Respiratory Tract, Signal Transduction, Transgenic Mice, Vaccine Development, Virulence Genes, Viruses and Virology
Specific Research Interests: Host-Pathogen Interactions
My research focuses on host-pathogen interactions involving respiratory viruses. More specifically, I am interested in studying the replication, pathogenesis, and transmission of influenza viruses. Areas of research include studies on humoral responses to influenza vaccines, development of model systems to study the effectiveness of vaccines against respiratory viruses, studies on virus regulation of innate and adaptive immune responses, and studies examining adaptation of viruses to new hosts.
PhD, Louisiana State University Health Sciences Center Shreveport
Langlois RA, Albrecht RA, Kimble B, Sutton T, Shapiro JS, Finch C, Angel M, Chua MA, Gonzalez-Reiche AS, Xu K, Perez D, García-Sastre A, tenOever BR. MicroRNA-based strategy to mitigate the risk of gain-of-function influenza studies. Nature biotechnology 2013 Sep; 31(9).
Rajsbaum R, Albrecht RA, Wang MK, Maharaj NP, Versteeg GA, Nistal-Villán E, García-Sastre A, Gack MU. Species-specific inhibition of RIG-I ubiquitination and IFN induction by the influenza A virus NS1 protein. PLoS pathogens 2012; 8(11).
Varble A, Albrecht RA, Backes S, Crumiller M, Bouvier NM, Sachs D, García-Sastre A, tenOever BR. Influenza A virus transmission bottlenecks are defined by infection route and recipient host. Cell host & microbe 2014 Nov; 16(5).
Sasaki S, Holmes TH, Albrecht RA, García-Sastre A, Dekker CL, He XS, Greenberg HB. Distinct cross-reactive B-cell responses to live attenuated and inactivated influenza vaccines. The Journal of infectious diseases 2014 Sep; 210(6).