Saadi Ghatan, MD
- SITE CHAIR, NEUROSURGERY, MOUNT SINAI WEST, MOUNT SINAI ST. LUKE'S | Mount Sinai St. Luke's
- ASSOCIATE PROFESSOR | Neurosurgery
- ASSOCIATE PROFESSOR | Pediatrics
Specialties:Neurosurgery, Pediatric Neurosurgery
Dr. Saadi Ghatan is the Chair of Neurosurgery at Mount Sinai West and Director of the Pediatric Neurosurgery Program of the Mount Sinai Health System. He is board certified in neurosurgery and pediatric neurosurgery, fellowship trained pediatric neurosurgery, and treats neonates, children, adolescents, and adults at the Mount Sinai Hospital, Mount Sinai West, and Mount Sinai Beth Israel.
Dr. Ghatan completed his residency and a fellowship in Pediatric Neurosurgery at Children’s Hospital in Seattle, Washington, as well as clinical and research fellowships in London, England.
His clinical interests include the treatment of nervous system conditions in the head, brain, spinal cord, and peripheral nerves. Specifically, he treats patients with epilepsy, brain and spinal cord tumors, arteriovenous malformations, craniofacial disorders, chiari malformations, syringomyelia, tethered spinal cords, spasticity, and hydrocephalus. He is an expert in minimally invasive neurosurgery with endoscopy and brain mapping with electrophysiological monitoring, and a leader in epilepsy surgery, including resective and palliative surgery (corpus callosotomy, VNS, RNS)
In collaboration with Steve Wolf, MD and Patty McGoldrick, NP, Dr. Ghatan spearheaded the growth and success of the Pediatric Epilepsy Surgery Program at Mount Sinai Beth Israel and Mount Sinai West. His most recent research includes studies on epilepsy surgery outcomes and surgical treatment for epilepsies associated with vascular malformations, autism, and strokes.
Dr. Ghatan has authored numerous chapters and has authored and co-authored peer reviewed manuscripts and book chapters and has presented posters and presentations at many regional, national and international meetings, including the American Epilepsy Society and the International Pediatric Epilepsy Surgery Conference.
He is consistently named a Top Doctor by Castle Connolly and a Super Doctor. He participates in a telemedicine program to bring neurosurgical care to residents of upstate New York, who have limited access to world class neurosurgical centers and may be unable to travel easily to a major center.
- Arteriovenous Malformations
- Brain Tumor And Brain Cancer
- Cavernous Malformations
- Chiari Malformation
- Intrathecal Pain Pump Insertion
- Minimally Invasive Spine Surgery
- Normal Pressure Hydrocephalus
- Seizure Disorder
- Spina Bifida
- Spinal Cord Tumors
MD, University of Washington
Residency, Surgery (General), University of Washington Medical Center
Residency, Neurosurgery, University of Washington Medical Center
Fellowship, Pediatric Neurosurg, Children's Hospital & Regional Medical Center
Epilepsy Surgery Outcomes
Epilepsy surgery outcomes and surgical treatment for epilepsies associated with vascular malformations, autism, and strokes.
Ellis JA, Anderson RC, O'Hanlon J, Goodman RR, Feldstein NA, Ghatan S. Internal cranial expansion surgery for the treatment of refractory idiopathic intracranial hypertension. Journal of neurosurgery. Pediatrics 2012 Jul; 10(1).
Mack WJ, Ghatan S. Congenital pterional dermal sinus in an 18-month-old child: case report. Neurosurgery 2007 Sep; 61(3).
Heyer GL, Millar WS, Ghatan S, Garzon MC. The neurologic aspects of PHACE: case report and review of the literature. Pediatric neurology 2006 Dec; 35(6).
Ghatan S. Surgery for epilepsy. Pediatric annals 2006 May; 35(5).
Ghatan S, Newell DW, Grady MS, Mirza SK, Chapman JR, Mann FA, Ellenbogen RG. Severe posttraumatic craniocervical instability in the very young patient. Report of three cases. Journal of neurosurgery 2004 Aug; 101(1 Suppl).
Anderson RC, Ghatan S, Feldstein NA. Surgical approaches to tumors of the lateral ventricle. Neurosurgery clinics of North America 2003 Oct; 14(4).
Blaha M, Lazar D, Winn RH, Ghatan S. Hemorrhagic complications of intracranial pressure monitors in children. Pediatric neurosurgery 2003 Jul; 39(1).
Mesiwala AH, Farrell L, Santiago P, Ghatan S, Silbergeld DL. The effects of hydrogen peroxide on brain and brain tumors. Surgical neurology 2003 May; 59(5).
Morrison RS, Kinoshita Y, Johnson MD, Ghatan S, Ho JT, Garden G. Neuronal survival and cell death signaling pathways. Advances in experimental medicine and biology 2002; 513.
Ghatan S, Ellenbogen RG. Pediatric spine and spinal cord injury after inflicted trauma. Neurosurgery clinics of North America 2002 Apr; 13(2).
Britz GW, Ghatan S, Spence AM, Berger MS. Intracarotid RMP-7 enhanced indocyanine green staining of tumors in a rat glioma model. Journal of neuro-oncology 2002 Feb; 56(3).
Ghatan S, Larner S, Kinoshita Y, Hetman M, Patel L, Xia Z, Youle RJ, Morrison RS. p38 MAP kinase mediates bax translocation in nitric oxide-induced apoptosis in neurons. The Journal of cell biology 2000 Jul; 150(2).
Silber JR, Blank A, Bobola MS, Ghatan S, Kolstoe DD, Berger MS. O6-methylguanine-DNA methyltransferase-deficient phenotype in human gliomas: frequency and time to tumor progression after alkylating agent-based chemotherapy. Clinical cancer research : an official journal of the American Association for Cancer Research 1999 Apr; 5(4).
Johnson MD, Kinoshita Y, Xiang H, Ghatan S, Morrison RS. Contribution of p53-dependent caspase activation to neuronal cell death declines with neuronal maturation. The Journal of neuroscience : the official journal of the Society for Neuroscience 1999 Apr; 19(8).
Silber JR, Bobola MS, Ghatan S, Blank A, Kolstoe DD, Berger MS. O6-methylguanine-DNA methyltransferase activity in adult gliomas: relation to patient and tumor characteristics. Cancer research 1998 Mar; 58(5).
Jünger EC, Newell DW, Grant GA, Avellino AM, Ghatan S, Douville CM, Lam AM, Aaslid R, Winn HR. Cerebral autoregulation following minor head injury. Journal of neurosurgery 1997 Mar; 86(3).
Berger MS, Ghatan S, Haglund MM, Dobbins J, Ojemann GA. Low-grade gliomas associated with intractable epilepsy: seizure outcome utilizing electrocorticography during tumor resection. Journal of neurosurgery 1993 Jul; 79(1).
Haglund MM, Berger MS, Kunkel DD, Franck JE, Ghatan S, Ojemann GA. Changes in gamma-aminobutyric acid and somatostatin in epileptic cortex associated with low-grade gliomas. Journal of neurosurgery 1992 Aug; 77(2).
Berger MS, Ghatan S, Geyer JR, Keles GE, Ojemann GA. Seizure outcome in children with hemispheric tumors and associated intractable epilepsy: the role of tumor removal combined with seizure foci resection. Pediatric neurosurgery; 17(4).
Nelson NF, Brown KB, Douthit DD, Ghatan S, Brown DG. Polyamine metabolism in isoproterenol-stimulated mouse salivary glands. Journal of dental research 1979 Jun; 58(6).