Samuel Sidi, PhD
img_Samuel Sidi
PROFESSOR | Cell, Developmental & Regenerative Biology
PROFESSOR | Medicine, Hematology and Medical Oncology
PROFESSOR | Oncological Sciences
Research Topics
Cancer Genetics, Cell Biology, DNA Repair, Drug Design and Discovery, Drug Resistance, Genomics, Molecular Biology, Signal Transduction, Tumor Suppressor Genes
Multi-Disciplinary Training Area
Cancer Biology [CAB], Development Regeneration and Stem Cells [DRS], Genetics and Genomic Sciences [GGS]

Cancer target discovery in zebrafish (genetic and chemical-genetic approaches), mechanism of action of targeted therapies, development of molecular diagnostics. For more information, please visit the Sidi Laboratory.

BS/MS, Paris VII University

Instructor, Harvard Medical School

MS, Paris VI University

PhD, Max-Planck Institute for Developmental Biology, University of Tubingen, and Paris VI University

Postdoctoral fellowship, Dana-Farber Cancer Institute, Harvard Medical School

2016

Pershing Square Sohn Prize for Young Investigators in Cancer Research

2012

Young Scientist Cancer Research Award

2011

Searle Scholar

2009

Claudia Adams Barr Award in Cancer Research

2004

French Foundation for Medical Research (FRM) Scholarship

2003

French Association for Cancer Research (ARC) Scholarship

Publications

Selected Publications

A noncanonical IRAK4-IRAK1 pathway counters DNA damage–induced apoptosis independently of TLR/IL-1R signaling. Yuanyuan Li, Richa B. Shah, Samanta Sarti, Alicia L. Belcher, Brian J. Lee, Andrej Gorbatenko, Francesca Nemati, Honglin Yu, Zoe Stanley, Mahbuba Rahman, Zhengping Shao, Jose M. Silva, Shan Zha, Samuel Sidi. Science Signaling

Sulfopin is a covalent inhibitor of Pin1 that blocks Myc-driven tumors in vivo. Christian Dubiella, Benika J. Pinch, Kazuhiro Koikawa, Daniel Zaidman, Evon Poon, Theresa D. Manz, Behnam Nabet, Shuning He, Efrat Resnick, Adi Rogel, Ellen M. Langer, Colin J. Daniel, Hyuk Soo Seo, Ying Chen, Guillaume Adelmant, Shabnam Sharifzadeh, Scott B. Ficarro, Yann Jamin, Barbara Martins da Costa, Mark W. Zimmerman, Xiaolan Lian, Shin Kibe, Shingo Kozono, Zainab M. Doctor, Christopher M. Browne, Annan Yang, Liat Stoler-Barak, Richa B. Shah, Nicholas E. Vangos, Ezekiel A. Geffken, Roni Oren, Eriko Koide, Samuel Sidi, Ziv Shulman, Chu Wang, Jarrod A. Marto, Sirano Dhe-Paganon, Thomas Look, Xiao Zhen Zhou, Kun Ping Lu, Rosalie C. Sears, Louis Chesler, Nathanael S. Gray, Nir London. Nature Chemical Biology

FANCI functions as a repair/apoptosis switch in response to DNA crosslinks. Richa B. Shah, Jennifer L. Kernan, Anya van Hoogstraten, Kiyohiro Ando, Yuanyuan Li, Alicia L. Belcher, Ivy Mininger, Andrei M. Bussenault, Renuka Raman, Ramanagouda Ramanagoudr-Bhojappa, Tony T. Huang, Alan D. D'Andrea, Settara C. Chandrasekharappa, Aneel K. Aggarwal, Ruth Thompson, Samuel Sidi. Developmental Cell

View All Publications

Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device, biotechnology companies, and other outside entities to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their outside financial relationships.

Dr. Sidi has not yet completed reporting of Industry relationships.

Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.