Steven G Coca, DO
img_Steven G Coca
PROFESSOR | Medicine, Nephrology
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Specialties
Internal Medicine, Nephrology
Dr. Coca is actively involved in clinical and translational research that focuses on using biomarkers to improve risk-stratification for outcomes in acute and chronic kidney disease. The development of prognostic and predictive biomarkers may aide future clinical trials, by serving as an enrichment strategy for enrollment, and may also serve as outcomes for early phase trials of novel interventions. He has leveraged existing cohorts with banked blood and urine samples, including the ACCORD, VA NEPHRON-D, CANVAS, and DAPA-CKD clinical trials, as well as the Mount Sinai BioMe Biobank and the UPenn Medicine Biobank to explore the prognostic, discriminative, and additional value of biomarkers in AKI and CKD. He has been an active investigator in several large NIH consortia, including the TRIBE-AKI, ASSESS-AKI, CKD Biocon, and Kidney Precision Medicine Project (KPMP). He plans to continue exploring these parameters in other large cohorts and then to design innovative trials employing biomarkers for facilitated enrollment and for better determination of efficacy of existing or new agents.

DO, University of New England College of Osteopathic Medicine

MS, Yale University Graduate School of Arts and Sciences

Residency, Internal Medicine, Yale University School of Medicine

Fellowship, Nephrology, Yale University School of Medicine

Certifications

American Board of Internal Medicine

2021

ASN

Midcareer Distinguished Researcher Award

2021

Top Reviewer Award

American Journal of Nephrology

2019

MSIP

“Deal of the Year Award” (for RenalytixAI; shared with Drs. Murphy and Nadkarni)

2018

Stanley L. Cohen Memorial Lecture & Award

Yale New Haven/Bridgeport Hospital Foundation

2017

Joseph R. Renda Memorial Award

Yale University School of Medicine

2013

AFMR 2013 Junior Physician Investigator Award

American Federation for Medical Research

2013

Junior Physician Investigator Award

American Federation for Medical Research

2008

T. Franklin Williams Scholar

2008

K23 Career Development Award

NIH/NIDDK

2008

NIH Loan Repayment Program

NIH

2008

ASN

ASP Junior Development Grant in Geriatric Nephrology

2007

Henry Christian Award

American Federation for Medical Research

2002

Intern of the Year

Yale Primary Care Internal Medicine Program

Midcareer Distinguished Researcher Award,

American Society of Nephrology

Top 5 Reviewer of the Year

Journal of the American Society of Nephrology

Top 5 Reviewer of the Year

Clinical Journal of the American Society of Nephrology

MSIP “Deal of the Year Award”

(for RenalytixAI; shared with Drs. Murphy and Nadkarni)

Top 5 Reviewer of the Year,

Journal of the American Society of Nephrology

Top 5 Reviewer of the Year,

Clinical Journal of the American Society of Nephrology

4D Technology Development Program Award

SINAInnovations

Henry Christian Award

American Federation for Medical Research

Publications

Selected Publications

The chromatin landscape of healthy and injured cell types in the human kidney. Debora L. Gisch, Michelle Brennan, Blue B. Lake, Jeannine Basta, Mark S. Keller, Ricardo Melo Ferreira, Shreeram Akilesh, Reetika Ghag, Charles Lu, Ying Hua Cheng, Kimberly S. Collins, Samir V. Parikh, Brad H. Rovin, Lynn Robbins, Lisa Stout, Kimberly Y. Conklin, Dinh Diep, Bo Zhang, Amanda Knoten, Daria Barwinska, Mahla Asghari, Angela R. Sabo, Michael J. Ferkowicz, Timothy A. Sutton, Katherine J. Kelly, Ian H. De Boer, Sylvia E. Rosas, Krzysztof Kiryluk, Jeffrey B. Hodgin, Fadhl Alakwaa, Seth Winfree, Nichole Jefferson, Aydın Türkmen, Joseph P. Gaut, Nils Gehlenborg, Carrie L. Phillips, Tarek M. El-Achkar, Pierre C. Dagher, Takashi Hato, Kun Zhang, Jonathan Himmelfarb, Matthias Kretzler, Shamim Mollah, Blue Lake, Alexander Morales, Isaac Stillman, Stewart Lecker, Steve Bogen, Ashish Verma, Guanghao Yu, Insa Schmidt, Joel Henderson, Laurence Beck, Pranav Yadati, Sushrut Waikar, Afolarin A. Amodu, Shana Maikhor, Titlayo Ilori, Mia R. Colona, Astrid Weins, Gearoid McMahon, Nir Hacohen, Anna Greka, Jamie L. Marshall, Paul J. Hoover, Vidya S. Viswanathan, Dana Crawford, Mark Aulisio, William Bush, Yijiang Chen, Anant Madabhushi, Charles O’Malley, Crystal Gadegbeku, Dianna Sendrey, Emilio Poggio, John O’Toole, John Sedor, Jonathan Taliercio, Lakeshia Bush, Leal Herlitz, Ellen Palmer, Jane Nguyen, Kassandra Spates-Harden, Leslie Cooperman, Stacey Jolly, Carissa Vinovskis, Andrew Bomback, Jonathan Barasch, Krzysztof Kiryluk, Paul Appelbaum, Vivette D’Agati, Cecilia Berrouet, Karla Mehl, Maya Sabatello, Ning Shang, Olivia Balderes, Pietro A. Canetta, Satoru Kudose, Joana de Pinho Gonçalves, Lukasz Migas, Raf Van de Plas, Roy Lardenoije, Laura Barisoni, Helmut Rennke, Abraham Verdoes, Angela Sabo, Debora Lidia Gisch, James Williams, Katherine Kelly, Kenneth Dunn, Michael Eadon, Michael Ferkowicz, Pierre Dagher, Seth Winfree, Sharon Bledsoe, Stephanie Wofford, Tarek Ashkar (El-Achkar), Timothy Sutton, William Bowen, Austen Slade, Elizabeth Record, Yinghua Cheng, Yashvardhan Jain, Bruce Herr, Ellen Quardokus, Ashley Wang, Celia Pamela Corona Villalobos, Chirag Parikh, Mohamed Atta, Steven Menez, Yumeng Wen, Alan Xu, Lauren Bernard, Camille Johansen, Sarah Chen, Sylvia Rosas, Isabel Donohoe, Jennifer Sun, Richard Knight, Anna Shpigel, Jack Bebiak, John Saul, Joseph Ardayfio, Robert Koewler, Roy Pinkeney, Taneisha Campbell, Evren Azeloglu, Girish Nadkarni, John He, Joji Tokita, Kirk Campbell, Marissa Patel, Sean Lefferts, Srinivas Ravi Iyengar, Stephen Ward, Steven Coca, Cijang He, Yuguang Xiong, Pottumarthi Prasad, Brad Rovin, John P. Shapiro, Samir Parikh, Sethu M. Madhavan, Jessica Lukowski, Dusan Velickovic, Ljiljana Pasa-Tolic, George (Holt) Oliver, Olga Troyanskaya, Rachel Sealfon, Weiguang Mao, Aaron Wong, Ari Pollack, Yury Goltsev, Brandon Ginley, Brendon Lutnick, Garry Nolan, Kavya Anjani, Tariq Mukatash, Zoltan G. Laszik, Baltazar Campos, Bijin Thajudeen, David Beyda, Erika Bracamonte, Frank Brosius, Gregory Woodhead, Katherine Mendoza, Nicole Marquez, Raymond Scott, Rebecca Tsosie, Milda Saunders, Adele Rike, E. Steve Woodle, Paul J. Lee, Rita R. Alloway, Tiffany Shi, Elena Hsieh, Jessica Kendrick, Joshua Thurman, Julia Wrobel, Laura Pyle, Petter Bjornstad, Nicholas Lucarelli, Pinaki Sarder, Amada Renteria, Ana Ricardo, Anand Srivastava, Devona Redmond, Eunice Carmona-Powell, James Bui, James Lash, Monica Fox, Natalie Meza, Ron Gaba, Suman Setty, Tanika Kelly, Chrysta Lienczewski, Dawit Demeke, Edgar Otto, Heather Ascani, Jeff Hodgin, Jennifer Schaub, John Hartman, Laura Mariani, Markus Bitzer, Michael Rose, Nikki Bonevich, Ninive Conser, Phillip McCown, Rachel Dull, Rajasree Menon, Rebecca Reamy, Sean Eddy, Ul Balis, Victoria Blanc, Viji Nair, Yongqun Oliver He, Zachary Wright, Becky Steck, Jinghui Luo, Renee Frey, Alyson Coleman, Dorisann Henderson-Brown, Jerica Berge, Maria Luiza Caramori, Oyedele Adeyi, Patrick Nachman, Sami Safadi, Siobhan Flanagan, Sisi Ma, Susan Klett, Susan Wolf, Tasma Harindhanavudhi, Via Rao, Amy Mottl, Anne Froment, Evan Zeitler, Peter Bream, Sara Kelley, Matthew Rosengart, Michele Elder, Paul Palevsky, Raghavan Murugan, Daniel E. Hall, Filitsa Bender, James Winters, John A. Kellum, Matthew Gilliam, Mitchell Tublin, Roderick Tan, Guanshi Zhang, Kumar Sharma, Manjeri Venkatachalam, Allen Hendricks, Asra Kermani, Jose Torrealba, Miguel Vazquez, Nancy Wang, Qi Cai, Richard Tyler Miller, Shihong Ma, Susan Hedayati, Andrew Hoofnagle, Artit Wangperawong, Ashley Berglund, Ashveena L. Dighe, Bessie Young, Brandon Larson, Brooke Berry, Charles Alpers, Christine Limonte, Christy Stutzke, Glenda Roberts, Ian de Boer, Jaime Snyder, Jimmy Phuong, Jonas Carson, Kasra Rezaei, Katherine Tuttle, Keith Brown, Kristina Blank, Natalya Sarkisova, Nichole Jefferson, Robyn McClelland, Sean Mooney, Yunbi Nam, Adam Wilcox, Christopher Park, Frederick Dowd, Kayleen Williams, Stephanie M. Grewenow, Stephen Daniel, Stuart Shankland, Annapurna Pamreddy, Hongping Ye, Richard Montellano, Shweta Bansal, Anil Pillai, Dianbo Zhang, Harold Park, Jiten Patel, Kamalanathan Sambandam, Mujeeb Basit, Natasha Wen, Orson W. Moe, Robert D. Toto, Simon C. Lee, Kavya Sharman, Richard M. Caprioli, Agnes Fogo, Jamie Allen, Jeffrey Spraggins, Katerina Djambazova, Mark de Caestecker, Martin Dufresne, Melissa Farrow, Anitha Vijayan, Brittany Minor, Gerald Nwanne, Joseph Gaut, Kristine Conlon, Madhurima Kaushal, Sabine M. Diettman, Angela M. Victoria Castro, Dennis Moledina, Francis P. Wilson, Gilbert Moeckel, Lloyd Cantley, Melissa Shaw, Vijayakumar Kakade, Tanima Arora, Sanjay Jain, Michael Rauchman, Michael T. Eadon. Nature Communications

Are biomarkers in acute kidney injury ready for prime time? The time is right for a second look. Chirag R. Parikh, Steven G. Coca. Kidney International

Genome-Wide Polygenic Risk Score for CKD in Individuals with APOL1 High-Risk Genotypes. Ha My T. Vy, Steven G. Coca, Ashwin Sawant, Ankit Sakhuja, Orlando M. Gutierrez, Richard Cooper, Ruth J.F. Loos, Carol R. Horowitz, Ron Do, Girish N. Nadkarni. Clinical Journal of the American Society of Nephrology

View All Publications

New Insights into the Diagnosis and Treatment of AKI in Patients with ADHF

Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device, biotechnology companies, and other outside entities to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their outside financial relationships.

Below are financial relationships with industry reported by Dr. Coca during 2023 and/or 2024. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.

Consulting or Other Professional Services: Examples include, but are not limited to, committee participation, data safety monitoring board (DSMB) membership

  • Axon Therapies
  • Boehringer-Ingelheim
  • Bayer
  • Nuwellis
  • Vifor
  • RenalytixAI
  • Reprieve Cardiovascular
  • 3ive

Equity (Stock or stock options valued at greater than 5% ownership of a publicly traded company or equity of any value in a privately held company)

  • RenalytixAI

Founder/Co-Founder/Partner:

  • RenalytixAI

Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.