Addiction Institute at Mount Sinai

Current Studies

Current Studies

Our research efforts are comprehensive in scope, using integrated research strategies across multiple disciplines including brain imaging, genomics, public health, and clinical trials with pharmacological agents and behavioral interventions. These studies include:

  • Clinical Studies (see below)

Active Projects include:

Outpatient Clinical Studies 

Substance

Title

Opioid

Acute and Short-Term Effects of CBD Administration on Cue-Induced Craving in Heroin-Dependent Drug-Abstinent Humans

 

BupeCare Platform for Enhanced Buprenorphine Treatment (MedicaSafe)

 

NIDA CTN protocol 006 - Implementation of ED-initiated Buprenorphine for Opioid Use Disorder

 

A Randomized, Double-Blind, Double-Dummy, Active-Controlled Study of Outpatients with Opioid Dependence Transitioned from 8 mg or Less of Sublingual Buprenorphine or Buprenorphine/Naloxone to Four Probuphine® Subdermal Implants

 

Prevention of Cardiovascular Medical Consequences of Drug Overdose

Stimulants

Using event-related potentials to longitudinally track cue-induced craving incubation in cocaine addicted individuals

 

Endothelial Dysfunction Markers in Cocaine-Dependent Patients Under Recent Abstinence

Alcohol

NIAAA NCIG-006: Randomized, Double-Blind, Placebo-Controlled Trial Of The Safety And Efficacy Of Horizant® (Gabapentin Enacarbil) Extended-Release Tablets For The Treatment Of Alcohol Use Disorder

 

 

Inpatient Clinical Studies 

Substance

Title

Opioid

A Phase 3 Study to Evaluate the Safety, Tolerability, and Efficacy of Naltrexone for use in Conjunction with Buprenorphine in Adults with Opioid Use Disorder Transitioning from Buprenorphine Maintenance Prior to First Dose of VIVITROL®

Cannabis

Synthetic Cannabinoid Use in Relation to Psychosis: Evaluation of Stress, Immune Function, and Genetics

 

Prevalence of Pain and Illicit Substance Use, as well as Attitudes Towards Medical Cannabinoids among Surgical Patients at the Mount Sinai Hospital

 

 

Neuroimaging Studies

Neuropsychoimaging of Addiction and Related Conditions

Neurocircuitry of Impaired insight in addiction

Effects of Early Life Stress on Brain Dysfunction in HIV+ Adults: An fMRI Study

 

 

Epidemiology Studies

DRIVE (Drug use and blood-borne Infections in Vietnam): Combined Prevention and Care to End the HIV Epidemic among People who Inject Drugs in Haiphong, Vietnam

Combined Prevention to Reduce Initiation into Injecting Drug Use

Risk Factors for AIDS among Drug Users: Getting Close to Zero

Evaluating ART for all HIV Seropositives: Can it work in the Hardest Cases?