LVAD Therapy: Exploring the Effect of Intramyocardial Injection of Mesenchymal Precursor Cells on Myocardial Function

ID Number 08-1078-00006

Principal Investigator(s)
Deborah V. Ascheim

Department(s) or Division(s)
Health Evidence and Policy

Description

The main purpose of this research is to determine whether injecting mesenchymal precursor cells (MPC) into the heart during surgery to implant a left ventricular assist device (LVAD) is safe and effective in improving heart function.  MPCs are normally present in human bone marrow, and have been shown to increase the development of blood vessels and new heart muscle cells in the heart. This study will test to see if these effects are enough to improve overall heart function.

People who are scheduled for surgery to implant an LVAD as either bridge-to-transplant (BTT) or as destination therapy (DT) may take part in this research study.



Contact Information
Janine Lynch, MPH
(212) 659-9631
janine.lynch@mountsinai.org

Recruiting Patients: No