A Randomized Effectiveness Trial of Early Hemodynamic Support in Patients Demonstrating a Double Low Combination of Mean-Arterial Pressure, and either End-Tidal Anesthetic Concentration, or Bispectral Index

ID Number 10-0111

Principal Investigator(s)
David L Reich

Department(s) or Division(s)
Anesthesiology

Description

The objective of this study is to test the effects of a computer system that uses information in the electronic anesthesia record to alert the anesthesia team to Double Low clinical conditions.  Double Low is a situation that occurs when both low blood pressure and deep general anesthesia are present at the same time.  In half the patients, the system generates an alert to the anesthesia team so long as the Double Low condition is present.  The project is designed to test whether these alerts affect the number of patients who are alive 90 days after surgery.  The project will also test whether the alerts affect the drugs given by the anesthesiologist, the blood pressure during surgery, and the hospital length of stay.  The study will enroll adults presenting for surgery under general anesthesia, except for those patients:
- Who choose not to participate;
- Having heart surgery;
- Having emergency surgery;
- Having surgery where low blood pressure is needed;
- Having already been enrolled in this study for a prior operation; and
- Where the depth of anesthesia is not measured using bispectral index (a brain wave monitor that is placed on the forehead).
Patients participating in this project otherwise undergo anesthesia and surgery in a normal fashion.



Contact Information
Patrick McCormick, MD
(212) 241-4080
anesthesia-research@mountsinai.org
anesthesia-research@mssm.edu

Recruiting Patients: Yes