Examining Dose-Related Effects of Oxytocin on Social Cognition Across Populations

ID Number 13-0340

Principal Investigator(s)
Maria de las Mercedes Perez-Rodriguez

Department(s) or Division(s)

Research Entity
Mood and Personality Disorders Research Program


The purpose of this study is to examine the effects of the administration of a drug called oxytocin, administered using a nasal spray, on social cognition in persons with schizotypal personality disorder (SPD) or borderline personality disorder (BPD). Social cognition refers to our ability to understand the social cues of people around us. Oxytocin has not yet been FDA approved for social cognition, but has been FDA approved for other indications, has been used in several recent studies as an investigational new drug. 

Many people who carry a diagnosis of SPD and/or BPD have trouble with social cognition. Information collected in this experiment may lead to a better understanding of the brain mechanisms involved in SPD and BPD and improve treatments for the psychological problems associated with these conditions.

Patients may qualify to take part in this research study, if they are between the ages of 18-60, have no serious medical illnesses, are not taking medication, and meet the diagnostic criteria for SPD or BPD.

Participation in this research study includes 3 study visits and is expected to last approximately between 8 to 12 weeks.

Contact Information
Amanda Fisher
(212) 241-2190

Recruiting Patients: Yes