A Phase III trial of Pelvic Radiation therapy vaginal cuff brachytherapy followed by paclitaxel/carboplatin in patients with high risk, early stage endometrial cancer (endometrium; uterus)
ID Number 05-0982-00249
Principal Investigator(s)Konstantin Zakashansky
Department(s) or Division(s)
Obstetrics, Gynecology, and Reproductive Science
Description
Radiation therapy can be given externally or with radioactive material placed directly into or near a tumor to kill tumor cells. Drugs used in chemotherapy, such as paclitaxel and carboplatin, also affect tumor cells by preventing them from growing and dividing. It is not yet known whether external pelvic radiation therapy is more effective than vaginal implant radiation therapy, paclitaxel, and carboplatin in treating patients with endometrial cancer. This randomized phase III trial is studying pelvic radiation therapy to see how well it works compared with vaginal implant radiation therapy, paclitaxel, and carboplatin in treating patients with high-risk stage I or stage II endometrial cancer.
Contact Information
Zakashansky, Konstantin, MD
konstantin.zakashansky@mssm.edu
Recruiting Patients: Yes