A Randomized, Double-Blind, Placebo-controlled Phase 3 Study of the Bruton's Tyrosine Kinase (BTK) Inhibitor, PCI-32765 (Ibrutinib), in Combination with Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) in Subjects With Newly Diagnosed Non-Germinal Center B-Cell Subtype of Diffuse Large B-Cell Lymphoma
ID Number 14-0558Principal Investigator(s)
Department(s) or Division(s)
Hematology and Medical Oncology
The purpose of this study is to compare the effects (both good and bad) of ibrutinib when it is given in combination with rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone (abbreviated as “R-CHOP”) to R-CHOP alone.
Recruiting Patients: Yes