Biomarkers of primary focal dystonias: structural-functional interactions

ID Number 09-0946

Principal Investigator(s)
Kristina Simonyan

Department(s) or Division(s)
Neurology

Description

The purpose of this study is to better understand the brain changes and genetic risks in patients with different types of primary focal dystonia (laryngeal dystonia singer’s dystonia pianist’s dystonia embouchure dystonia oromandibular dystonia writer’s cramp cervical dystonia and blepharospasm) compared to healthy subjects. We will also compare brain changes in patients with spasmodic dysphonia and writer’s cramp to brain changes in patients with cervical dystonia and blepharospasm. The causes of primary focal dystonia are unknown. Recent studies found changes in brain function in patients with dystonias which may play an important role in the development of this disorder.



Contact Information
Estee Rubien-Thomas
(212) 241-1438
estee.rubien-thomas@mssm.edu

Recruiting Patients: Yes