Craniosynostosis Network

ID Number 13-0147

Principal Investigator(s)
Ethylin W Jabs

Department(s) or Division(s)
Genetics and Genomic Sciences

Description

Craniosynostosis is a common birth defect that requires surgical treatment during the first year of life to prevent severe neurologic deficits. An international team of investigators will generate large genomic and expression datasets on mouse models and humans with craniosynostosis by using state-of-the-art imaging, genetic, and developmental & systems biology approaches to quantitatively model novel pathways and networks involved in embryonic and postnatal development of craniosynostosis. Quantitative and functional validations of these predictions will provide insights into the etiology and potential therapeutic targets for craniosynostosis and many bone-related disorders.



Contact Information
Ethylin Jabs
(212) 241-7056
ethylin.jabs@mssm.edu

Recruiting Patients: Yes