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Your search for "Nervous System" returned 22 results:

A multicenter, randomized, double-blind, parallel-group, placebo-controlled variable treatment duration study evaluating the efficacy and safety of Siponimod (BAF312) in patients with secondary progressive multiple sclerosis
Principal Investigator(s): Aaron Miller

A Phase 3 Multicenter Multinational Randomized Double-blind Placebo-controlled Study to Evaluate the Efficacy and Safety of Patisiran (ALN-TTR02) in Transthyretin (TTR)-Mediated Polyneuropathy (Familial Amyloidotic Polyneuropathy – FAP) (APOLLO)
Principal Investigator(s): Peter Gorevic

Multicenter, randomized, double-blind, double-dummy, active-comparator, event-driven, superiority phase III study of secondary prevention of stroke and prevention of systemic embolism in patients with a recent Embolic Stroke of Undetermined Source (ESUS), comparing rivaroxaban 15 mg once daily with aspirin 100 mg (NAVIGATE ESUS)
Principal Investigator(s): Tansy, Aaron

A phase 1/2 Trial assessing the safety and efficacy of bilateral intraputaminal and intranigral administration of cere-120 (adeno-associated virus serotype 2 (AAV2)-Neirturin (NTN) in subjects with Idiopathic Parkinson's disease
Principal Investigator(s): Cho, Catherine

An open label, add-on trial of cetirizine for patients with neuromyelitis optica
Principal Investigator(s): Ilana Katz-Sand

CD Flex: An Open-Label, Non-Inferiority Study Evaluating the Efficacy and Safety of Two Injection Schedules of Xeomin® (incobotulinumtoxinA) [Short Flex vs. Long Flex] in Subjects with Cervical Dystonia < 10 Weeks of Benefit from OnabotulinumtoxinA Treatment
Principal Investigator(s): Winona Tse, MD

Cortical-Subcortical Interaction in Parkinson’s Disease
Principal Investigator(s): Kristina Simonyan, M.D., Ph.D.

Open-label proof-of-concept trial to evaluate the response to Acthar Gel therapy in patients with MS relapses who have failed to make adequate recovery after treatment with IV methylprednisolone
Principal Investigator(s): Aaron Miller

Evaluation of quality of life in adult patients with MS switching from injectable therapy i.e. Interferon (Avonex, Betaseron, Extavia, Rebif) or Copaxone® (glatiramer acetate) to oral medication Tecfidera® (BG00012) and their caregivers and evaluating their physical disability, cognitive function and adherence
Principal Investigator(s): Aliza Ben-Zacharia

A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study Investigating the Efficacy and Safety of CVT-301 (Levodopa Inhalation Powder) in Parkinson’s Disease Patients With Motor Response Fluctuations (OFF Phenomena)
Principal Investigator(s): Winona Tse

A Phase IIIB, Multicentre, Randomised, Double-Blind, Placebo-Controlled Study Evaluating the Efficacy and Safety of Dysport Using 2 mf Dilution in Adults with Cervical Dystonia
Principal Investigator(s): Winona Tse, MD

Evaluation of quality of life in adult patients with MS switching from injectable therapy i.e. Interferon (Avonex, Betaseron, Extavia, Rebif) or Copaxone® (glatiramer acetate) to oral medication Gilenya® (fingolimod) and their caregivers
Principal Investigator(s): Aliza Ben-Zacharia

Phase III Randomized Study of Chimeric Anti-GC2 in high risk neuroblastoma following myeloablative therapy and autologous stem cell rescue (Protocol - ANBL0032) (Brain)
Principal Investigator(s): Birte Wistinghausen

An open-label, 12 months safety and efficacy study of Levodopa- carbidopa intestinal gel in levodopa-responsive subjects with advanced parkinson's disease and severe motor-fluctuations despite optimized treatment with available parkinson's disease medications
Principal Investigator(s): Cho, Catherine

A Multicenter Global Observational Study to Collect Information on Safety and to Document the Drug Utilization of Tecfidera™ (Dimethyl Fumarate) When Used in Routine Medical Practice in the Treatment of Multiple Sclerosis (ESTEEM)
Principal Investigator(s): Ilana Katz-Sand

Defining the Microbiome in a Stratified Population of Multiple Sclerosis Patients
Principal Investigator(s): Patrizia Casaccia

Study of Eculizumab in Patients with GMG
Principal Investigator(s): Sivak, Mark

Impact of intraoperative blood pressure on cognitive performance in patients with and without hypertension a prospective observational study
Principal Investigator(s): Deiner, Stacie

MISTIE III - A phase III, Randomized, Open Label, 500-Subject Clinical Trial of Minimally Invasive Surgery Plus rt-PA in the Treatment of Intraccebral Hemorrhage
Principal Investigator(s): J Mocco

Genetics Studies of Moebius Syndrome
Principal Investigator(s): Jabs, Ethylin

Screening for Depression in Patients with Multiple Sclerosis
Principal Investigator(s): Ben-Zacharia, Aliza

A Phase 2/3 Randomized Double-Blind Placebo-Controlled Study to Assess the Efficacy and Safety of ISIS 420915 in Patients with Familial Amyloid Polyneuropathy
Principal Investigator(s): Peter Gorevic