Alzheimer's Disease Research Center
The Mount Sinai Alzheimer's Disease Research Center (ADRC) is a nationally renowned center funded by the National Institute on Aging. The mission of the center is to provide expertise in basic and clinical research for investigators both within and beyond Mount Sinai community. The ADRC is made up of five cores and three projects.
- Administrative Core: Organizes the resources of the ADRC. Through the many national and international collaborations we can provide guidance on available data sets, tissue and cell repositories and funding opportunities. We also offer small pilot awards.
- Clinical Core: Conducts clinical, neuropsychological, genetic, biomarker and diagnostic characterization of a clinical cohort. The core cohort is available for research studies and the core faculty can provide expertise in developing evaluations for other settings and studies.
- Clinical Core Satellite: Conducts outreach and recruitment activities in our urban, minority community to accomplish enrollment of a diverse population to our clinical core. These participants receive the same clinical, neuropsychological, genetic, biomarker and diagnostic characterization. The core cohort is available for research studies and the core faculty can provide expertise in developing evaluations for other settings and studies.
- Data Core: Oversees the data collection and transmission of our data to a national data base and can provide consultation for study design and statistical analysis for this and associated projects.
- Neuropathology Core: Conduct neuropathological analysis from postmortem brain tissue specimens from persons with Alzheimer’s disease and comparison groups. Core personnel are available to advise investigators on brain region and case selection applicable to specific hypotheses. Data on select quantitative neuropathologic variables relevant to Alzheimer’s disease is provided to investigators as applicable.
- Education & Information Transfer Core: Provides community outreach, education and training including memory improvement classes and memory screenings. The core also offers physician and healthcare trainee education about dementia. The Core is also available to offer research training as regards the use of cognitive testing in research.