Recognition and Publications

Baron, Margaret M.D., Ph.D.

Fraser ST, Isern J, and Baron MH. (2006) Maturation and enucleation of primitive erythroblasts is accompanied by changes in cell surface antigen expression patterns during mouse embryogenesis. Blood, Epub ahead of press.

Willey S, Ayuso-Sacido A, Zhang H, Fraser ST, Sahr KE, Adlam MJ, Kyba M, Daley GQ, Keller G, and Baron MH. (2006). Acceleration of mesoderm development and expansion of hematopoietic progenitors in differentiating ES cells by the mouse Mix-like homeodomain transcription factor. Blood 107, 3122-3130.

Bieker, James Ph.D.

Adelman CA, Chattopadhyay S, and Bieker JJ. (2002). The BMP/BMPR/Smad pathway directs expression of the erythroid-specific EKLF and GATA1 transcription factors during embryoid body differentiation in serum-free media. Development 129, 539-549.

Manwani D, Galdass M, and Bieker JJ, Altered Regulation of ß-like Globin Genes by a Redesigned Erythroid Transcription Factor, submitted (2006)

Frasch, Manfred Ph.D.

Lee HH, and Frasch M. (2005). Nuclear integration of positive Dpp signals, antagonistic Wg inputs and mesodermal competence factors during Drosophila visceral mesoderm induction. Development 132, 1429-1442.

Reim I, and Frasch M. (2005). The Dorsocross T-box genes are key components of the regulatory network controlling early cardiogenesis in Drosophila. Development 132, 4911-4925.

Frenette, Paul M.D.

Katayama Y, Battista M, Kao WM, Hidalgo A, Peired AJ, Thomas SA, and Frenette PS. (2006). Signals from the sympathetic nervous system regulate hematopoietic stem cell egress from bone marrow. Cell 124, 407-421.

Hidalgo A, and Frenette PS. (2005). Enforced fucosylation of neonatal CD34+ cells generates selectin ligands that enhance the initial interactions with microvessels but not homing to bone marrow. Blood 105, 567-575.

Germano, Isabelle M.D.

Uzzaman M, Benveniste RJ, Keller G, and Germano IM. (2005). Embryonic stem cell-derived astrocytes: a novel gene therapy vector for brain tumors. Neurosurg Focus 19, E6.

Ghaffari, Saghi M.D., Ph.D.

Ghaffari S, Jagani Z, Kitidis C, Lodish HF, and Khosravi-Far R. (2003). Cytokines and BCR-ABL mediate suppression of TRAIL-induced apoptosis through inhibition of forkhead FOXO3a transcription factor. Proc Natl Acad Sci U S A 100, 6523-6528.

Ghaffari S, Kitidis C, Zhao W, Marinkovic D, Fleming MD, Luo B, Marszalek J, and Lodish HF. (2006). AKT induces erythroid-cell maturation of JAK2-deficient fetal liver progenitor cells and is required for Epo regulation of erythroid-cell differentiation. Blood 107, 1888-1891.

Huntley, George W. Ph.D.

Brock JH, Elste A, and Huntley GW. (2004). Distribution and injury-induced plasticity of cadherins in relationship to identified synaptic circuitry in adult rat spinal cord. J Neurosci 24, 8806-8817.

Nagy V, Bozdagi O, Matynia A, Balcerzyk M, Okulski P, Dzwonek J, Costa, RM, Silva, AJ, Kaczmarek L, and Huntley GW. (2006). Matrix metalloproteinase-9 is required for hippocampal late-phase long-term potentiation and memory. J Neurosci 26, 1923-1934.

Lin, Riegh-Yi Ph.D.

Lin RY, Kubo A, Keller GM, and Davies TF. (2003). Committing embryonic stem cells to differentiate into thyrocyte-like cells in vitro. Endocrinology 144, 2644-2649.

Merad, Miriam M.D., Ph.D.

Ginhoux F, Tacke F, Angeli V, Bogunovic M, Loubeau M, Dai XM, Stanley ER, Randolph GJ, and Merad M. (2006). Langerhans cells arise from monocytes in vivo. Nat Immunol 7, 265-273.

Mende I, Karsunky H, Weissman IL, Engleman EG, and Merad M. (2006). Flk2+ myeloid progenitors are the main source of Langerhans cells. Blood 107, 1383-1390.

Sokol, Sergei Y. Ph.D.

Hikasa H, and Sokol SY. (2004). The involvement of Frodo in TCF-dependent signaling and neural tissue development. Development 131, 4725-4734.

Brott BK, and Sokol SY. (2005). A vertebrate homolog of the cell cycle regulator Dbf4 is an inhibitor of Wnt signaling required for heart development. Dev Cell 8, 703-715.

Snoeck, Hans M.D., Ph.D.

Kumar R, Langer JC, and Snoeck HW. (2006). Transforming growth factor-beta2 is involved in quantitative genetic variation in thymic involution. Blood 107, 1974-1979.

Langer JC, Kumar R, and Snoeck HW. (2006). Age-related accumulation of a novel CD44 + CD25lowgammadelta T-cell population in hematopoietic organs of the mouse. J Gerontol A Biol Sci Med Sci 61, 568-571.

Venugopalan, Nair Ph.D.

Nair VD. (2006). Activation of p53 signaling initiates apoptotic death in a cellular model of Parkinson's disease. Apoptosis 11, 955-966.

Nair VD, Yuen T, Olanow CW, and Sealfon SC. (2004). Early single cell bifurcation of pro- and antiapoptotic states during oxidative stress. J Biol Chem 279, 27494-27501.

Weinstein, Daniel Ph.D.

Suri C, Haremaki T, and Weinstein DC. (2005). Xema, a foxi-class gene expressed in the gastrula stage Xenopus ectoderm, is required for the suppression of mesendoderm. Development 132, 2733-2742.

Weinstein DC. (2005).  Mesodermal differentiation: signal integration during development.  Science STKE tr 23.

Wilson, Patricia D. Ph.D.

Polgar K, Burrow CR, Hyink DP, Fernandez H, Thornton K, Li X, Gusella GL, and Wilson PD. (2005). Disruption of polycystin-1 function interferes with branching morphogenesis of the ureteric bud in developing mouse kidneys. Dev Biol 286, 16-30.

Wilson PD. (2004). Polycystic kidney disease: new understanding in the pathogenesis. Int J Biochem Cell Biol 36, 1868-1873.

Wolosin, Jose Ph.D.

Budak MT, Alpdogan OS, Zhou M, Lavker RM, Akinci MA, and Wolosin JM. (2005). Ocular surface epithelia contain ABCG2-dependent side population cells exhibiting features associated with stem cells. J Cell Sci 118, 1715-1724.

Wolosin JM, Budak MT, and Akinci MA. (2004). Ocular surface epithelial and stem cell development. Int J Dev Biol 48, 981-991.

Woo, Savio Ph.D.

Kubo A, Shinozaki K, Shannon JM, Kouskoff V, Kennedy M, Woo S, Fehling HJ, and Keller G. (2004). Development of definitive endoderm from embryonic stem cells in culture. Development 131, 1651-1662.

Chen L, and Woo SL. (2005). Complete and persistent phenotypic correction of phenylketonuria in mice by site-specific genome integration of murine phenylalanine hydroxylase cDNA. Proc Natl Acad Sci U S A 102, 15581-15586.