Pricing
Pricing for sequencing and microarray services is current as of April 2012. The costs outlined below are for Icahn School of Medicine investigators or associated laboratories. Non-profit institutions are encouraged to submit samples for processing.
We do extend our services to external academic, nonprofit and commercial institutions. For details please contact us at inquiry-gcf@mssm.edu.
Next Generation Sequencing Prices
Illumina Sequencing
| Instrument | Length | Read Type | Price Per Lane |
|---|---|---|---|
| HiSeq 2000 | 50nt | Single Read | $1,025 |
| HiSeq 2000 | 50nt | Paired End | $1,600 |
| HiSeq 2000 | 100nt | Single Read | $1,500 |
| HiSeq 2000 | 100nt | Paired End | $2,250 |
| MiSeq | 50nt | Single Read | $825 |
| MiSeq | 150nt | Paired End | $1,235 |
Pacific Biosciences Sequencing
| Instrument | Movie Time | Price Per SMRT Cell |
|---|---|---|
| PacBio RS | 45 minutes x 2 movies | $300 |
| PacBio RS | 90 minutes x 1 movie | $300 |
Next Generation Sample Preparation Prices
| Sequencing Platform | Sample Type | Description | Cost Per Sample |
|---|---|---|---|
| Illumina | Genomic DNA | Standard Library with Index-read multiplexing | $250 |
| Illumina | Genomic DNA | Whole-Exome Capture for one sample | $915 |
| Illumina | Genomic DNA | Whole Exome Capture for two samples | $710 |
| Illumina | Genomic DNA | Whole Exome Capture for 3 samples (e.g. family trio)* | $510 |
| Illumina | Chromatin IP’ed DNA | Standard Library with Index-read multiplexing | $250 |
| Illumina | Total RNA | RNA-Seq Library: Poly(A) RNA capture with cDNA library for multiplex sequencing | $300 |
| Illumina | Total RNA (Eukaryotic or Prokaryotic) | rRNA Depletion with RiboZero and cDNA library for multiplex sequencing | $400 |
| Illumina | User prepared or captured RNA >200ng | cDNA library preparation for multiplex sequencing | $300 |
| Pacific Biosciences | Genomic DNA | Standard library with no multiplexing barcodes | $350 |
*Batch of three genomic DNA libraries will be barcoded and captured together, and then sequenced together
If you would like to prepare your DNA or RNA libraries, we recommend using Illumina sample preparation kits. We have negotiated a Mount Sinai wide discount of 10%, please use quote # 20120312AM2052 when ordering. View full price list [PDF]
Illumina BeadArray Pricing
To calculate project costs, please add chip purchase costs and the associated processing costs. Users are required to purchase their own BeadArrays and submit them along with the samples. The Genomics Core charges only the sample processing costs, which are as follows.
Illumina BeadArray Sample Preparation, Hybridization and Scanning
| Array Type | Sample Volume | Price Per Sample |
|---|---|---|
| Genotyping | <50 | $130 |
| Genotyping | 51-96 | $65 |
| Genotyping | 97-500 | $45 |
| Genotyping | 501-1000 | $35 |
| Genotyping | >1,001 | $25 |
| Expression Profiling | - | $140 |
| Methylation Profiling | - | $125 |
Illumina BeadArray Chip Prices
The table below indicates Illumina list prices as of March 2012. Please refer to Illumina website Illumina genotyping chips, Illumina Gene Expression chips, Illumina Methylation chips for current prices and full product list. We have worked with Illumina for special Mount Sinai discount prices. Please use quote 20120127AM301 when ordering. View full price list [PDF]
| Application | Chip Name | Genome Targets | Cost Per Chip | Samples Per Chip | Min.Chips to Order |
|---|---|---|---|---|---|
| Genotyping | HumanOmniExpress-12 WG-311-1120 |
700K | $3,000 | 48 | 4 |
| Genotyping | HumanCytoSNP-12 WG-320-2101 |
300K | $1,860 | 12 | 1 |
| Genotyping | HumanExome v1.1 WG-353-1101 |
245K | $900 | 12 | 4 |
| Genotyping | Linkage-24 WG-32-140 |
6K | $1,080 | 24 | 2 |
| Genotyping | HumanOmni1S-8 WG-311-1114 |
1.2M | $2,800 | 8 | 2 |
| Genotyping | HumanOmni2.5-8v1 WG-311-2511 |
2.5M | $3,200 | 8 | 2 |
| Genotyping | HumanOmni5 WG-311-5001 |
4.3M | $2,320 | 4 | 4 |
| Genotyping | HumanOmni5Exome v1.0 WG-311-5010 |
4.5M | $2,476 | 4 | 4 |
| Genotyping | HumanOmniExpress Exome v1.0 WG-350-2206 |
950K | $2,312 | 8 | 2 |
| Gene Expression | HumanHT-12 v4.0 BD-103-0204 |
47K | $900 | 12 | 2 |
| Gene Expression | MouseWG-6 v2.0 BD-201-0202 |
45K | $960 | 6 | 2 |
| Gene Expression | &MouseRef-8 v2.0 BD-202-0202 |
25K | $800 | 8 | 2 |
| Gene Expression | HumanMethylation450 WG-314-1001 |
450K | $3,600 | 12 | 4 |
Sanger Sequencing
Research samples: $6/sequencing reaction
For clinical Sanger sequencing, please contact us at sanger-gcf@mssm.edu.
Agilent BioAnalyzer
| Chip Type | Sensitivity | Cost Per Sample |
|---|---|---|
| DNA 1000 | Nanograms | $10 |
| DNA High Sensitivity | Picograms | $15 |
| RNA Nano | Nanograms | $10 |
| RNA Pico | Picograms | $15 |