Research

Bordner KA, Kitchen RR, Carlyle B, George ED, Mahajan MC, et al. (2011) Parallel declines in cognition, motivation, and locomotion in aging mice: association with immune gene upregulation in the medial prefrontal cortex. Exp Gerontol 46: 643-659.

Chen Y, Zhu J, Lum PY, Yang X, Pinto S, et al. (2008) Variations in DNA elucidate molecular networks that cause disease. Nature 452: 429-435.

Chin CS, Sorenson J, Harris JB, Robins WP, Charles RC, et al. (2011) The origin of the Haitian cholera outbreak strain. N Engl J Med 364: 33-42.

Emilsson V, Thorleifsson G, Zhang B, Leonardson AS, Zink F, et al. (2008) Genetics of gene expression and its effect on disease. Nature 452: 423-428.

Pandey G, Atluri G, Steinbach M, Myers CL, Kumar V (2009) An association analysis approach to biclustering. Proceedings of the 15th ACM SIGKDD international conference on Knowledge discovery and data mining. ACM. pp. 677-686

Horak CE, Mahajan MC, Luscombe NM, Gerstein M, Weissman SM, et al. (2002) GATA-1 binding sites mapped in the beta-globin locus by using mammalian chIp-chip analysis. Proc Natl Acad Sci U S A 99: 2924-2929.h

Karmakar S, Mahajan MC, Schulz V, Boyapaty G, Weissman SM (2010) A multiprotein complex necessary for both transcription and DNA replication at the β-globin locus. EMBO J 29: 3260-3271.

Mahajan MC, Karmakar S, Newburger PE, Krause DS, Weissman SM (2009) Dynamics of alpha-globin locus chromatin structure and gene expression during erythroid differentiation of human CD34( ) cells in culture. Exp Hematol 37: 1143-1156.e1143.

Linderman MD, Collins JD, Wang H, Meng TH (2008) Merge: a programming model for heterogeneous multi-core systems. Proceedings of the 13th international conference on Architectural support for programming languages and operating systems. ACM. pp. 287-296.

Linderman MD, Bruggner R, Athalye V, Meng TH, Asadi NB, et al. (2010) High-throughput Bayesian network learning using heterogeneous multicore computers. Proceedings of the 24th ACM International Conference on Supercomputing. ACM. pp. 95-104.

Pandey G, Myers CL, Kumar V (2009) Incorporating functional inter-relationships into protein function prediction algorithms. BMC Bioinformatics 10: 142.

Pandey G, Zhang B, Chang AN, Myers CL, Zhu J, et al. (2010) An integrative multi-network and multi-classifier approach to predict genetic interactions. PLoS Comput Biol 6.

Rasko DA, Webster DR, Sahl JW, Bashir A, Boisen N, et al. (2011) Origins of the E. coli strain causing an outbreak of hemolytic-uremic syndrome in Germany. N Engl J Med 365: 709-717.

Schadt EE (2009) Molecular networks as sensors and drivers of common human diseases. Nature 461: 218-223.

Schadt EE, Friend SH, Shaywitz DA (2009) A network view of disease and compound screening. Nat Rev Drug Discov 8: 286-295.

Schadt EE, Linderman MD, Sorenson J, Lee L, Nolan GP (2010) Computational solutions to large-scale data management and analysis. Nat Rev Genet 11: 647-657.

Schadt EE, Molony C, Chudin E, Hao K, Yang X, et al. (2008) Mapping the genetic architecture of gene expression in human liver. PLoS Biol 6: e107.

Schadt EE, Turner S, Kasarskis A (2010) A window into third-generation sequencing. Hum Mol Genet 19: R227-240.

Su WL, Kleinhanz RR, Schadt EE (2011) Characterizing the role of miRNAs within gene regulatory networks using integrative genomics techniques. Mol Syst Biol 7: 490.

Wang K, Narayanan M, Zhong H, Tompa M, Schadt EE, et al. (2009) Meta-analysis of inter-species liver co-expression networks elucidates traits associated with common human diseases. PLoS Comput Biol 5: e1000616.

Wontakal SN, Guo X, Will B, Shi M, Raha D, et al. (2011) A large gene network in immature erythroid cells is controlled by the myeloid and B cell transcriptional regulator PU.1. PLoS Genet 7: e1001392.9

Yang X, Deignan JL, Qi H, Zhu J, Qian S, et al. (2009) Validation of candidate causal genes for obesity that affect shared metabolic pathways and networks. Nat Genet 41: 415-423.

Yang X, Zhang B, Molony C, Chudin E, Hao K, et al. (2010) Systematic genetic and genomic analysis of cytochrome P450 enzyme activities in human liver. Genome Res 20: 1020-1036.

Zhang W, Zhu J, Schadt EE, Liu JS (2010) A Bayesian partition method for detecting pleiotropic and epistatic eQTL modules. PLoS Comput Biol 6: e1000642.

Zhu J, Zhang B, Smith EN, Drees B, Brem RB, et al. (2008) Integrating large-scale functional genomic data to dissect the complexity of yeast regulatory networks. Nat Genet 40: 854-861.