Bieker Lab - Publications
Recognition and Publications
|1994-1999||Scholar of the Leukemia Society of America|
|2006||Visiting Scientist, Weatherall Institute of Molecular Medicine, Oxford University Oxford UK|
|2006-2007||Interim Director, Black Family Stem Cell Institute, The Icahn School of Medicine|
|2007||Vice-Chair, Red Cell Gordon Research Conference|
|2008||Tohoku Medical Society Testimonial, Tohoku University, Sendai, Japan|
|2009||Chair, Red Cell Gordon Research Conference|
T. Sengupta, N. Cohet, F. Morle, and J. J. Bieker, Distinct modes of gene regulation by a cell-specific transcriptional activator, Proceedings of the National Academy of Sciences, 106, 4213-4218 (2009).
T. Sengupta, K. Chen, E. Milot, and J. J. Bieker, Acetylation of EKLF is essential for epigenetic modification and transcriptional activation of the ß-globin locus, Molecular and Cellular Biology, 28, 6160-6170 (2008).
J. J. Bieker, Blood group antigens reveal their maker, Blood, 112, 1554-1555 (2008).
F. Lohmann and J. J. Bieker, Activation of Eklf expression during hematopoiesis by Gata2 and Smad5 prior to erythroid commitment, Development, 135, 2071-2082 (2008). [highlighted as an In this Issue preview]
K. J. Quadrini, E. Gruzglin, and J. J. Bieker, Non-random subcellular distribution of variant EKLF in erythroid cells, Experimental Cell Research, 314, 1595-1604 (2008).
D. Manwani and J. J. Bieker, The Erythroblastic Island, Current Topics in Developmental Biology, 82, 23-53 (2008).
M. P. Frontelo*, D. Manwani*, M. Galdass, H. Karsunky, F. Lohmann, P. G. Gallagher, and J. J. Bieker, Novel role for EKLF in megakaryocyte lineage commitment, Blood, 110, 3871-3880 (2007). [*co-first authors] [highlighted as an Inside Blood preview]
M. Siatecka, L. Xue, and J. J. Bieker, Sumoylation of EKLF Promotes Transcriptional Repression and Is Involved in Inhibition of Megakaryopoiesis, Molecular and Cellular Biology, 27, 8547-8560 (2007).
D. Manwani. M. Galdass, and J. J. Bieker, Altered Regulation of ß-like Globin Genes by a Redesigned Erythroid Transcription Factor, Experimental Hematology, 35, 39-47 (2007).
K. J. Quadrini and J. J. Bieker, EKLF/KLF1 is Ubiquitinated and its Stability is Regulated by Activation Domain Sequences Through the 26S Proteasome, FEBS Letters, 580, 2285-2293 (2006).
J. J. Bieker, Probing the Onset and Regulation of Erythroid Cell-Specific Gene Expression, Mount Sinai Journal of Medicine, 72, 333-338 (2005).
J. J. Bieker, An unexpected entry into the globin real estate market, Blood, 106, 2230-2231 (2005).
H. Im, J. A. Grass, K. D. Johnson, S. Kim, M. E. Boyer, A. N. Imbalzano, J. J. Bieker, and E. H. Bresnick, Chromatin Domain Activation Via GATA-1 Utilization of a Small Subset of Dispersed GATA Motifs Within a Broad Chromosomal Region, Proc. Natl. Acad. Sci., 102, 17065-17070 (2005).
L. Xue, X. Chen, Y. Chang, and J. J. Bieker, Regulatory Elements of the EKLF Gene That Direct Erythroid Cell-specific Expression During Mammalian Development, Blood, 103, 4078-4083 (2004).
X. Chen and J. J. Bieker, Stage-specific Repression by the EKLF Transcriptional Activator, Molecular and Cellular Biology, 24, 10416-10424 (2004).
C. A. Adelman, S. Chattopadyay, and J. J. Bieker, The BMP/BMPR/Smad Pathway Directs Expression of the Erythroid-Specific EKLF and GATA1 Transcription Factors During Embryoid Body Differentiation in Serum-free Media, Development, 129, 539-549 (2002).
K. J. Quadrini and J. J. Bieker, Krüppel-like Zinc Fingers Bind to Nuclear Import Proteins and are Required for Efficient Nuclear Localization of EKLF, Journal of Biological Chemistry, 277, 32243-32252 (2002).
W. Zhang, S. Kadam, B. M. Emerson, and J. J. Bieker, Site-Specific Acetylation by p300/CBP Regulates Erythroid Krüppel-like Factor (EKLF) Transcriptional Activity via its Interaction with the SWI/SNF Complex, Molecular and Cellular Biology, 21, 2413-2422 (2001).
X. Chen and J. J. Bieker, Unanticipated Repression Function Linked to Erythroid Krüppel-like Factor (EKLF), Molecular and Cellular Biology, 21, 3118-3125 (2001).
J. J. Bieker, Krüppel-like Factors: Three Fingers in Many Pies, J. Biol. Chem., 276, 34355-34358 (2001).
J. J. Bieker, EKLF and the development of the erythroid lineage, in Transcription Factors: Normal and Malignant Development of Blood Cells (ed. K. Ravid and J. Licht) (2000).