Meet Our Team
Ethylin Wang (Mimi) Jabs, MD
Ethylin (Mimi) is the director of the laboratory. She received her MD, pediatric, and medical genetic training at The Johns Hopkins University. She was the Dr. Frank V. Sutland Professor of Pediatric Genetics, Professor of Pediatrics, Medicine, and Plastic Surgery, and Director of the Center for Craniofacial Development and Disorders at the Johns Hopkins School of Medicine.
Currently, she is the Vice Chair of the Department of Genetics and Genomic Sciences and Chief of the Division of Medical Genetics and Genomics at Icahn School of Medicine. The research focus of the laboratory is on developmental genetics. The group is investigating the molecular basis of human malformations, especially craniofacial disorders. She very much enjoys the adventure of original research and mentoring others.
Current Laboratory Members
Claudia completed her Doctorate of Pharmacy in Marseilles, France and specialized in the Pharmaceutical Industry. She moved to the US in 2007 and enrolled in the MA of Biotechnology of Columbia University. After her MA, she was working in the Physiology and Cellular Biophysics lab at Columbia University Medical Center working on immune cells, especially neutrophils. She then joined the Neurology department, working on Alzheimer disease. She joined the Jabs laboratory in 2014 and is engaged in working on transgenic mouse models.
Erin Brittain serves as the administrative assistant for the Jabs group. Her duties include maintaining the websites and database of samples received by research participants. Erin also serves as the educational coordinator for the Department of Genetics and Genomic Sciences. She completed her graduate studies in classical voice in the Peabody Conservatory at Johns Hopkins University. In addition to working at Mount Sinai, Erin is pursuing a career in music.
Monica completed her undergraduate degree in Biology as well as a Master’s degree in Biology with a focus on genetics at Universidad del Valle in Cali, Colombia. She then moved to the U.S. where she joined the Gene Discovery Lab in Mount Sinai. During this time, Monica participated in multiple projects including gene mapping, large scale SNP analysis, and genotyping for Mendelian and complex disorders, including Setleis syndrome, Tukel syndrome and Crohn’s disease. Monica then completed her Master’s degree in Genetic Counseling at Mount Sinai, graduating in 2012. Monica is now a practicing Genetic Counselor at Elmhurst Hospital in New York, while building databases for our lab.
Greg received his PhD from The University of Queensland, Australia. His postdoctoral training has been in the laboratories of Lee Niswander (Memorial Sloan-Kettering Cancer Center, NY) studying chick and mouse embryological limb development, and Claudio Basilico (NYU School of Medicine, NY) studying interactions between the Fgf and Wnt signaling pathways, including the role of Sox2, in osteoblasts. While there, he developed a strong interest in craniofacial development, and worked on the Apert craniosynostosis syndrome. He joined the Jabs group in 2011 to pursue further research into the molecular processes and tissue interactions underlying a variety of craniosynostosis syndromes. He is currently an Assistant Professor in the Department.
William (Bill) A. Paznekas
Bill has had experience in immunology and molecular biology over a period of 35 years from his work at Johns Hopkins University. His research endeavors include identification of disease genes and comparative genomics. He has assisted—and continues to assist—in the experimental design of many of the projects in the laboratory. Bill received the Institute of Genetic Medicine Staff Award in 2004 from the Johns Hopkins University. His focus recently has been to find contributing genetic factors to the phenotypic variability of oculodentodigital dysplasia.
Ying received her PhD in Endocrinology and Metabolism from Shanghai Jiao Tong University in China, studying the function of osteoglycin in the regulation of the hypothalamic-pituitary-adrenal (HPA) axis. She started her career in the Department of Endocrinology at Mount Sinai as a visiting scholar working on brain regulation of insulin sensitivity and bone turnover. She joined the Jabs laboratory in 2014 and will work on making induced pluripotent stem cells (iPSCs) to study disease pathogenesis.
Meng received his PhD in Biochemistry and Molecular Biology from Peking Union Medical College in China, studying chromatin remodeling in cell differentiation. He started his postdoctoral training in 2009 in the Center for Molecular Cardiology at Mount Sinai. There, he studied heart development with mouse genetics, focusing on the function of epigenetic regulators in the development of the cardiac conduction system. Meng has a strong interest in gene regulation in development. He joined the Jabs group in 2014 and works on projects to elucidate molecular mechanisms of human malformation disorders.
Xiaoqian came to the lab as a postdoctoral fellow in June 2009. She obtained her DMD and PhD degree from Hospital and School of Stomatology, Wuhan University in China. Her research centers on the underlying mechanisms of craniofacial malformations. Her main focus includes functional studies on Roberts-SC phocomelia syndrome, and in addition, using mouse genetic approaches to elucidate mutant genes and their pathways that are responsible for normal and perturbed development of craniofacial skeleton and other organs. Xiaoqian received a 2011 award from the Society of Craniofacial Genetics for her poster, “Candidate genes analysis of nonsyndromic sagittal craniosynostosis.” She is an Instructor in the Department.
Past Laboratory Members
Nicholas Heitman (past laboratory trainee)
Nick graduated from the University of Wisconsin-Madison with a major in Microbiology. At UW, he studied metabolic integration and redundancy in Salmonella enterica under the mentorship of Dr. Diana Downs. After he received his Masters in Biomedical Sciences performing research on effects of fibroblast growth factor receptor in brain development in the Jabs laboratory, he entered the Mount Sinai MD/PhD program. He is interested in investigating the molecular bases of human genetic diseases.
Ying-Li Wang (past laboratory faculty)
Yingli received her DMD from Xi'an Medical University and PhD from Peking University of China. She finished her postdoctoral training at the Johns Hopkins University. She has risen to the position of Assistant Professor at Icahn School of Medicine. Her research focuses on studying the pathogenesis and molecular mechanism of human genetic malformations with craniofacial abnormalities, including Apert, Beare-Stevenson cutis gyrata and Saethre-Chotzen syndromes, by analyzing transgenic mouse models. She left the Jabs lab to receive her DMD from University of Pennsylvania and become a board certified dentist in the US.
Bryn Webb (past laboratory faculty)
Bryn Webb completed the combined Pediatrics/Medical Genetics 5-year residency program at Mount Sinai. She has had a strong interest in basic science research since her first laboratory internship while in college at the age of 17. Bryn has received numerous scholarships and fellowships to work in research labs at a variety of institutions including Harvard Medical School and the National Institutes of Health. Bryn joined the Jabs lab in 2009 and is currently working on projects studying Moebius and Goldenhar syndromes. In 2011 Bryn received an award from the Moebius Syndrome Foundation and the Rappaport Memorial Resident Research Award. She is a physician-scientist and an Assistant Professor in the Department.
Jinglan Zhang (past laboratory trainee)
Jinglan received his PhD in 2009 from Baylor College of Medicine in Biochemistry and Molecular Biology. He is receiving his postdoctoral training in Clinical Biochemical Genetics and Clinical Molecular Biology at Mount Sinai and now an Assistant Professor in the Department of Molecular and Human Genetics at Baylor. He is continuing to collaborate with the Jabs laboratory. Jinglan is very interested in developing new methodology to discover human disease biomarkers.
Xueyan (Sherry) Zhou (past laboratory member)
Xueyan (Sherry) acquired her MD and MS in Microbiology from Hebei Medical University of P.R. China. She had been working as an assistant researcher in the Department of Dermatology at Mount Sinai for 5 years. She was a senior lab technician of the Jabs laboratory from 2009-to 2014. Her research focused on studying the transgenic mouse models of craniofacial abnormalities including Apert, Beare-Stevenson cutis gyrata and Saethre-Chotzen syndromes. She is currently a laboratory manager at Wake Forest University.
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