Influenza viruses are globally important human pathogens infecting up to 500 million people annually. With the recent emergence of highly pathogenic avian influenza (HPAI) strains, there is a pressing need to understand the pathogenesis of influenza A and develop vaccines and therapies.
The García-Sastre laboratory investigates the molecular biology of influenza viruses and several other negative strand RNA viruses. Dr. García-Sastre’s lab developed reverse genetics techniques that allow for the generation of recombinant influenza viruses from plasmid DNA. This work has led to major breakthroughs in revealing the molecular basis of influenza virus pathogenicity.
Adolfo García-Sastre, PhD
Professor of Microbiology and of Medicine (Infectious Diseases)
Co-Director, Global Health and Emerging Pathogens Institute
Department of Microbiology
Icahn School of Medicine at Mount Sinai
Annenberg Building Floor 16 Room 90
1468 Madison Avenue
New York, NY 10029
Adolfo García-Sastre, PhD, is the Co-Director of the Global Health and Emerging Pathogens Institute, the Irene and Dr. Arthur M. Fishberg Professor of Medicine (Infectious Diseases), and Professor of Microbiology.Learn more