Quantitative urinary succinylacetone analysis is used in diagnosing and monitoring patients with tyrosinemia type I. This work up should also include plasma amino acid analysis and urine organic acids analysis. Succinylacetone analysis is performed by gas chromatography and mass spectrometry after organic solvent extraction and trimethylsilane derivatization.
5-10 ml urine, random or preferably morning first void, in a clean container without preservatives.
Shipping: Freeze and ship overnight frozen on dry ice.
Turnaround Time: 5 days
CPT Codes: 80500, 82570, 83921, 83789
Consent Form: Biochemical Consent [PDF]
Requisition Form: General Test Requisition [PDF]