Recognition and Publications

Budhwar R, Fang G, Hirsch JP. Kelch repeat proteins control yeast PKA activity in response to nutrient availability. Cell Cycle. 2011 Mar 1;10(5).

Budhwar R, Lu A, Hirsch JP. Nutrient control of yeast PKA activity involves opposing effects on phosphorylation of the Bcy1 regulatory subunit. Mol Biol Cell. 2010 Sep 8.

Niranjan T, Guo X, Victor J, Lu A, Hirsch JP. Kelch repeat protein interacts with the yeast Galpha subunit Gpa2p at a site that couples receptor binding to guanine nucleotide exchange. J Biol Chem. 2007 Aug 17;282(33):24231-8.

Lu A, Hirsch JP. Cyclic AMP-Independent Regulation of Protein Kinase A Substrate Phosphorylation by Kelch Repeat Proteins. Eukaryot Cell. 2005 Nov;4(11):1794-800.

Ohi MD, Vander Kooi CW, Rosenberg JA, Ren L, Hirsch JP, Chazin WJ, Walz T, Gould KL. Structural and functional analysis of essential pre-mRNA splicing factor Prp19p. Mol Cell Biol. 2005 Jan;25(1):451-60.

Peng L, Mirshahi T, Zhang H, Hirsch JP, Logothetis DE. Critical determinants of the G protein gamma subunits in the Gbetagamma stimulation of G protein-activated inwardly rectifying potassium (GIRK) channel activity. J Biol Chem. 2003 Dec 12;278(50):50203-11.

Batlle M, Lu A, Green DA, Xue Y, Hirsch JP. Krh1p and Krh2p act downstream of the Gpa2p G(alpha) subunit to negatively regulate haploid invasive growth. J Cell Sci. 2003 Feb 15;116(Pt 4):701-10.

Kim J, Bortz E, Zhong H, Leeuw T, Leberer E, Vershon AK, Hirsch JP. Localization and signaling of G(beta) subunit Ste4p are controlled by a-factor receptor and the a-specific protein Asg7p. Mol Cell Biol. 2000 Dec;20(23):8826-35.

Lorenz MC, Pan X, Harashima T, Cardenas ME, Xue Y, Hirsch JP, Heitman J. The G protein-coupled receptor gpr1 is a nutrient sensor that regulates pseudohyphal differentiation in Saccharomyces cerevisiae. Genetics. 2000 Feb;154(2):609-22.

Kim J, Couve A, Hirsch JP. Receptor inhibition of pheromone signaling is mediated by the Ste4p Gbeta subunit. Mol Cell Biol. 1999 Jan;19(1):441-9.

Kim J, Hirsch JP. A nucleolar protein that affects mating efficiency in Saccharomyces cerevisiae by altering the morphological response to pheromone. Genetics. 1998 Jun;149(2):795-805.

Xue Y, Batlle M, Hirsch JP. GPR1 encodes a putative G protein-coupled receptor that associates with the Gpa2p Galpha subunit and functions in a Ras-independent pathway. EMBO J. 1998 Apr 1;17(7):1996-2007.

Couve A, Hirsch JP. Loss of sustained Fus3p kinase activity and the G1 arrest response in cells expressing an inappropriate pheromone receptor. Mol Cell Biol. 1996 Aug;16(8):4478-85.

Yu Y, Hirsch JP. An essential gene pair in Saccharomyces cerevisiae with a potential role in mating. DNA Cell Biol. 1995 May;14(5):411-8.