Immunity – New Study Shows Tissue Resident Macrophages Arise Independently of Circulating Monocytes
A new study published in Immunity by Merad Laboratory reveals that tissue resident macrophages arise independently of circulating monocytes.
Daigo Hashimoto1,2*, Andrew Chow1,2,5*, Clara Noizat1,6, Pearline Teo7, Mary Beth Beasley3,4, Marylene Leboeuf1,2, Christian D. Becker1,2,4, Peter See7, Jeremy Price1,2, Daniel Lucas5, Melanie Greter1,8, Arthur Mortha1,2, Scott W. Boyer9, E. Camilla Forsberg9,10, Masato Tanaka11, Nico van Rooijen12, Adolfo García-Sastre13,14,15, E. Richard Stanley16, Florent Ginhoux7, Paul S. Frenette5†, Miriam Merad1,2† . Tissue resident macrophages self-maintain locally throughout adult life with minimal contribution from circulating monocytes. Immunity. 2013 Apr 18;38(4):792-804.
Learn more about the study.