Projects and Grants

NIH Grants

1999. "Alzheimer's Disease Research Center at Icahn School of Medicine". 2P50-AG05138-06. 04/01/99-03/31/04 NIH/NIA. N.K. Robakis Director of Project #4: "Vesicular Localization and Function of PS1 Protein." $156,000/year direct costs

2000. National Institutes of Health (NIA). 1 R01 AG17926-01. Project Title: "presenilin 1 is a component of the adherens junctions" N.K.Robakis, Principal Investigator. 05/01/2000-04/30/2005. $225,000/year direct costs

2001. National Institutes of Health (NIA) Grant 2 R01-AG08200-14; "A cadherin/PS1- gamma-secretase Signal Transduction pathway." N.K.Robakis, Principal Investigator. 9\01\01-8\31\06. 225,000/year direct costs

2003. National Institutes of Health (NINDS) Grant 1 R01 NS047229-01. "PS1 activates the PI3K/Akt cell survival pathway" N.K.Robakis, Principal Investigator. 12\01\03-11\30\08. 250,000/year direct costs ($2,116,665 total costs). (expected to be funded. Score: 14.3%)

Non-NIH Grants

2001. Alzheimer Association Investigator Initiated Research Grant IIRG-01-3124 (N. K. Robakis, PI). “Synaptic expression and function of PS1.” 09/01/01-08/31/04. $240,000 total costs

2002. American Health Assistance Foundation (P. Marambaud, PI): Role of the presenilin-1-mediated cleavage of E-cadherin 04/01/02-03/31/04. $200,000 total costs. Cadherins and PS1

2003. American Health Assistance Foundation (A. Georgakopoulos PI). 04/01/03-03/31/05. $200,000 total costs. PS1-mediated cleavage of Ephrins and Eph receptors.

2004. Alzheimer's Association New Investigator Research Grant NIRG-04-1011 (L. Baki, PI). "PS1 prevents development of AD pathological hallmarks via PI3K signaling." 9/1/04-8/31/06. $100,000 total costs