Hierarchical Organization of the Central Voice Control
Brain networks responsible for (I) laryngeal, articulatory and respiratory coordination, (II) vocalization initiation and motivation, (III) voluntary vocal motor control. Read More
The Simonyan Laboratory uses multi-modal neuroimaging approach to study central mechanisms of vocal motor control and to identify neuroimaging, neuropathological, genetic and environmental correlates of primary focal dystonias.
Spasmodic Dysphonia Research Program
Funded by the National Institute on Deafness and other Communication Disorders, National Institutes of Health (NIDCD/NIH, Grant# R01DC011805), we are conducting a 5-year study to determine the relationship between brain changes and genetic factors in spasmodic dysphonia. We hope that the outcome of this study may lead to better clinical management of this disorder, including its improved detection, accurate diagnosis, and assessment of risk to develop spasmodic dysphonia in family members.
Our other research study, also funded by the National Institute on Deafness and other Communication Disorders, National Institutes of Health (NIDCD/NIH, Grant# R01DC012545), aims to identify brain abnormalities in spasmodic dysphonia and vocal tremor as the basis for characterization of central mechanisms underlying symptom improvement following the use of sodium oxybate, a novel pharmacological agent for treatment of ethanol-responsive dystonia and tremor. We expect that the findings of this study would have a direct impact on improvement of clinical management of spasmodic dysphonia and vocal tremor.
Click here to read more about these and other ongoing studies.
Become a Research Participant
Click here to learn more about the study and complete a survey for study eligibility.
New Insights are Revealed about the Neurotransmitter Function in Primary Dystonia
December 18, 2013 - Two studies led by Dr. Simonyan identified the role of dopaminergic abnormalities in primary focal dystonias, such as spasmodic dysphonia and writer's cramp
2013 Siemens Competition
October 18, 2013 - Stephen Leong becomes a semifinalist in 2013 Siemens Competition with his research project on brain networks controlling speech production, which he conducted in Simonyan Laboratory
Head of Laboratory
Kristina Simonyan, MD, PhD
Associate Professor of Neurology and Otolaryngology
Estee Rubien-Thomas, BA
One Gustave L. Levy Place
Department of Neurology
New York, NY 10029
1468 Madison Avenue
2nd Floor, Room 2-210E
New York, NY 10029