Hierarchical Organization of the Central Voice Control
Brain networks responsible for (I) laryngeal, articulatory and respiratory coordination, (II) vocalization initiation and motivation, (III) voluntary vocal motor control. Read More
The Simonyan Laboratory uses multi-modal neuroimaging approach to study central mechanisms of vocal motor control and to identify neuroimaging and neuropathological correlates of primary focal dystonias.
Kristina Simonyan, MD, PhD, from the Icahn School of Medicine at Mount Sinai, has received more than $5 million from the National Institutes of Health (NIH) to study spasmodic dysphonia (SD). Read more
Spasmodic Dysphonia Research Program
Funded by the National Institute on Deafness and other Communication Disorders, National Institutes of Health (NIDCD/NIH, Grant# R01DC011805), we are conducting a 5-year study to determine the relationship between brain changes and genetic factors in spasmodic dysphonia. We hope that the outcome of this study may lead to better clinical management of this disorder, including its improved detection, accurate diagnosis, and assessment of risk to develop spasmodic dysphonia in family members.
Our other research study, also funded by the National Institute on Deafness and other Communication Disorders, National Institutes of Health (NIDCD/NIH, Grant# R01DC012545), aims to identify brain abnormalities in spasmodic dysphonia and vocal tremor as the basis for characterization of central mechanisms underlying symptom improvement following the use of sodium oxybate, a novel pharmacological agent for treatment of ethanol-responsive dystonia and tremor. We expect that the findings of this study would have a direct impact on improvement of clinical management of spasmodic dysphonia and vocal tremor.
Click here to read more about these and other ongoing studies.
Become a Research Participant
Click here to learn more about the study and complete a survey for study eligibility.
Head of Laboratory
Kristina Simonyan, MD, PhD
Associate Professor of Neurology and Otolaryngology
Amanda Pechman, BA
1468 Madison Avenue
Department of Neurology
2nd Floor, Room 2-210C
New York, NY 10029