Simonyan Laboratory

The Simonyan Laboratory uses multi-modal neuroimaging approach to study central mechanisms of vocal motor control and to identify neuroimaging, neuropathological, genetic and environmental correlates of primary focal dystonias.

Spasmodic Dysphonia Research Program

Funded by the National Institute on Deafness and other Communication Disorders, National Institutes of Health (NIDCD/NIH, Grant# R01DC011805), we are conducting a 5-year study to determine the relationship between brain changes and genetic factors in spasmodic dysphonia. We hope that the outcome of this study may lead to better clinical management of this disorder, including its improved detection, accurate diagnosis, and assessment of risk to develop spasmodic dysphonia in family members.

Our other research study, also funded by the National Institute on Deafness and other Communication Disorders, National Institutes of Health (NIDCD/NIH, Grant# R01DC012545), aims to identify brain abnormalities in spasmodic dysphonia and vocal tremor as the basis for characterization of central mechanisms underlying symptom improvement following the use of sodium oxybate, a novel pharmacological agent for treatment of ethanol-responsive dystonia and tremor. We expect that the findings of this study would have a direct impact on improvement of clinical management of spasmodic dysphonia and vocal tremor. 

Click here to read more about these and other ongoing studies.

Become a Research Participant

Click here to learn more about the study and complete a survey for study eligibility.

Contact Us

Head of Laboratory
Kristina Simonyan, MD, PhD
Associate Professor of Neurology and Otolaryngology
Tel: 212-241-0656
Send e-mail

Research Contact
Estee Rubien-Thomas, BA
Research Associate
Tel: 212-241-1438
Fax: 646-537-8628
Send e-mail 

Mailing Address
One Gustave L. Levy Place 
Department of Neurology
Box 1137
New York, NY 10029

Laboratory Location 
Annenberg Building
1468 Madison Avenue
2nd Floor, Room 2-210E
New York, NY 10029